Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/47486
Título: | In-vivo demonstration of the suitability of piezoelectric stimuli for bone reparation |
Autor(es): | Ribeiro, Clarisse Correia, D. M. Rodrigues, I. Guardão, L. Guimarães, S. Soares, R. Lanceros-Méndez, S. |
Palavras-chave: | Bone regeneration Piezoelectric stimuli Smart materials Tissue engineering |
Data: | 15-Dez-2017 |
Editora: | Elsevier 1 |
Revista: | Materials Letters |
Citação: | Ribeiro, Clarisse; Correia, D. M.; Rodrigues, I.; Guardão, L.; Guimarães, S.; Soares, R.; Lanceros-Méndez, S., In-vivo demonstration of the suitability of piezoelectric stimuli for bone reparation. Materials Letters, 209, 118-121, 2017 |
Resumo(s): | he potential of piezoelectric biomaterials for bone tissue engineering is demonstrated. This work proves that the use of piezoelectric poly(vinylidene fluoride) (PVDF), able to provide electrical stimuli upon mechanical solicitation to the growing cells, enhances bone regeneration in vivo. Poled and non-poled β-PVDF films and randomly oriented electrospun fiber mats have been used to test their osteogenic properties in Wistar rats by analyzing new bone formation in vivo. After 4 weeks, defect implanted with poled β-PVDF films demonstrated significantly more defect closure and bone remodeling, showing the large potential of piezoelectric biomaterials for bone repair. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/47486 |
DOI: | 10.1016/j.matlet.2017.07.099 |
ISSN: | 0167-577X |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_46890_1.pdf Acesso restrito! | 1,09 MB | Adobe PDF | Ver/Abrir |