Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/47004
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Baran, E. T. | por |
dc.contributor.author | Pirraco, Rogério P. | por |
dc.contributor.author | Cerqueira, Mariana Teixeira | por |
dc.contributor.author | Marques, A. P. | por |
dc.contributor.author | Retolaza, Aritz | por |
dc.contributor.author | Merino, S. | por |
dc.contributor.author | Neves, N. M. | por |
dc.contributor.author | Reis, R. L. | por |
dc.date.accessioned | 2017-11-03T11:38:06Z | - |
dc.date.issued | 2015-04 | - |
dc.date.submitted | 2017-02 | - |
dc.identifier.citation | Baran E. T., Pirraco R. P., Cerqueira M. T., Marques A. P., Retolaza A., Merino S., Neves N. M., Reis R. L. Depth (Z-axis) control of cell morphologies on micropatterned surfaces, Journal Of Bioactive And Compatible Polymers, Vol. 30, Issue 5, pp. 1-13, doi:10.1177/0883911515580354, 2015 | por |
dc.identifier.issn | 0883-9115 | por |
dc.identifier.uri | https://hdl.handle.net/1822/47004 | - |
dc.description.abstract | In this study, cell responses on micropatterned films that were changing in groove–ridge widths and pattern depth were investigated to compare the degree of size effects from X–Y and Z planes. Poly(caprolactone) films with five different groove–ridge sizes and three pattern depths were prepared by hot embossing technique. In general, the morphologies of osteoblast cell were not changed noticeably by the size changes in groove–ridges with the same depth size. However, cell morphologies were changed significantly when pattern depths were increased from 1.35 to 4.95µm. Also, the cell morphology change between different groove–ridges was significant when the pattern depth was small (1.35µm), and these effects were diminished or masked when the pattern depth was increased to 4.95µm. Linear regression analysis further clarifies that unit size changes in depth may affect cell length and orientation rates 2.4 and 4 times, respectively, in comparison to rates obtained from X–Y planes. | por |
dc.description.sponsorship | This work was supported by the Portuguese Foundation for Science and Technology scholarship (SFRH/BPD/30768/2006). E.T.B. was financially supported by European Union Seventh Framework Program (FP7/2007-2013) under grant agreement no. NMP4-SL2009-229292 (“Find & Bind”). | por |
dc.language.iso | eng | por |
dc.publisher | SAGE | por |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F30768%2F2006/PT | por |
dc.relation | FP7/2007-2013 | por |
dc.relation | NMP4-SL2009-229292 | por |
dc.rights | restrictedAccess | por |
dc.subject | Cell guiding | por |
dc.subject | Cell morphology | por |
dc.subject | Lithography | por |
dc.subject | Micropatterning | por |
dc.subject | Pattern depth | por |
dc.title | Depth (Z-axis) control of cell morphologies on micropatterned surfaces | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://journals.sagepub.com/doi/pdf/10.1177/0883911515580354 | por |
dc.comments | http://3bs.uminho.pt/node/19005 | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 13 | por |
oaire.citationIssue | 5 | por |
oaire.citationVolume | 30 | por |
dc.date.updated | 2017-09-25T15:01:05Z | - |
dc.identifier.eissn | 1530-8030 | por |
dc.identifier.doi | 10.1177/0883911515580354 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Bioactive and Compatible Polymers | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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19005-Depth (Z-axis) control of cell morphologies on micropatterned surfaces.pdf Acesso restrito! | 1,16 MB | Adobe PDF | Ver/Abrir |