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TitleTendon stem cell niche
Author(s)Almeida, Raquel Carvalho Ferreira Costa
Gonçalves, Ana Isabel Silva
Gershovich, Pavel
Rodrigues, Márcia T.
Reis, R. L.
Gomes, Manuela E.
KeywordsCell therapy
Extracellular matrix
Regenerative medicine
Tendon healing/repair
Tendon stem/progenitor cells
Issue dateSep-2015
PublisherSpringer Verlag
CitationCosta-Almeida R., Gonçalves A. I., Gershovich P., Rodrigues M. T., Reis R. L., Gomes M. E. Tendon stem cell niche, Tissue-Specific Stem Cell Niche, pp. 221-244, 2196-8985, 2015.
Abstract(s)Tendon stem cells constitute a heterogeneous population of stem and progenitor cells that is involved in tendon formation and healing. The basic understanding of the interactions between tendon cells and their surroundings can enable the development of improved regenerative therapies. In this chapter, the main characteristics of their microenvironment â niche â are reviewed. In particular, the importance of signaling molecules and extracellular matrix (ECM) are highlighted, focusing on their potential role in tendon regeneration. 
TypeBook part
DescriptionSeries: "Stem cell biology and regenerative medicine"
AccessRestricted access (UMinho)
Appears in Collections:3B’s - Capítulos de Livros/Book Chapters

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