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TitleHybrid alginate-based cryogels for life science applications
Author(s)Barros, Alexandre António Antunes
Quraishi, Sakeena
Martins, Marta
Gurikov, Pavel
Subrahmanyam, Raman
Smirnova, Irina
Duarte, Ana Rita C.
Reis, R. L.
CO2 gelation
Issue dateAug-2016
PublisherWiley-VCH Verlag
JournalChemie Ingenieur Technik
CitationBarros A. A., Quraishi S., Martins M., GuriKov P., Subrahmanyam R., Smirnova I., Duarte A. R. C., Reis R. L. Hybrid Alginate-Based Cryogels for Life Science Applications, Chemie Ingenieur Technik, Vol. 88, Issue 11, pp. 0-0, doi:10.1002/cite.201600096, 2016
Abstract(s)This work presents a novel route toward porous scaffolds for tissue engineering and regenerative medicine (TERM) appli- cations. Hybrid cryogels with gelatin, gellan gum, carboxymethylcellulose, and lignin were prepared by a two-step process. Textural properties of the cryogels were analyzed by SEM and micro-computed tomography. The results indicated that rapid freezing retained sample shape and yielded macroporous materials. The mechanical properties of the cryogels were characterized in compression mode. Cytotoxicity studies indicated that the hybrid-alginate cryogels did not present cyto- toxicity and have the potential to be used in TERM.
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Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals

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