Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/39114
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Fernandes, Soraia P. | por |
dc.contributor.author | Proença, M. Fernanda R. P. | por |
dc.contributor.author | Wilson, Cristina Pereira | por |
dc.contributor.author | Dias, Alice | por |
dc.date.accessioned | 2015-12-21T19:04:41Z | - |
dc.date.issued | 2015-05-08 | - |
dc.identifier.uri | https://hdl.handle.net/1822/39114 | - |
dc.description.abstract | [Excerpt] The imidazole nucleus is present in a significant number of biomolecules and the inclusion of this moiety in organic scaffolds is considered an important synthetic strategy in drug discovery.[1] 5-Aminoimidazoles are interesting building blocks in medicinal chemistry since they are key components in many bioactive molecules and their derivatives showed a wide pharmacological potential as anticancer drugs.[1] The hydrazones constitute an important class of biological active drug molecules due to their wide range of pharmacological properties that include antitumoral activities.[2] Amidrazone derivatives could be considered very promising in the perspective of new drug discovery, because they are very effective as building blocks to obtain various heterocycles.[2,3] The α-hydrazononitriles are a special case of compounds belonging to the family of hydrazones that is less common in the literature, but has a great interest due to their pharmacological applications.[4] (...) | por |
dc.description.sponsorship | FCT (NMR portuguese network); FCT and FEDER-COMPETE-QREN-EU [Pest-C/QUI/UI0686/2011 (FCOMP-01-0124-FEDER-022716)] | por |
dc.language.iso | eng | por |
dc.relation | Pest-C/QUI/UI0686/2011 | por |
dc.rights | restrictedAccess | por |
dc.subject | Química Orgânica | por |
dc.subject | Biologia | por |
dc.title | The synthesis of novel 5-aminoimidazoles derivatives with anticancer activity | por |
dc.type | conferenceAbstract | - |
dc.peerreviewed | yes | por |
sdum.publicationstatus | published | por |
oaire.citationConferenceDate | 8 Maio 2015 | por |
sdum.event.type | congress | por |
oaire.citationConferencePlace | Braga, Portugal | por |
oaire.citationTitle | 2nd Symposium on Medicinal Chemistry of the University of Minho | por |
dc.subject.fos | Ciências Naturais::Ciências Químicas | por |
dc.subject.fos | Ciências Naturais::Ciências Biológicas | por |
sdum.conferencePublication | 2nd Symposium on Medicinal Chemistry of the University of Minho | por |
Aparece nas coleções: | CDQuim - Comunicações e Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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SQM_The Synthesis of Novel 5-Aminoimidazoles derivatives with potential anticancer activity - Soraia Fernandes.pdf Acesso restrito! | 91,81 kB | Adobe PDF | Ver/Abrir |