Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/38869
Título: | Dynamic piezoelectric stimulation enhances osteogenic differentiation of human adipose stem cells |
Autor(es): | Ribeiro, Clarisse Marta Oliveira Pärssinen, J. Sencadas, Vítor João Gomes Silva Correia, Vítor Manuel Gomes Miettinen, S. Hytönen, V. P. Lanceros-Méndez, S. |
Palavras-chave: | Electroactive polymer Stem cell Osteogenesis Dynamic condition dynamic conditions |
Data: | 2015 |
Editora: | Wiley |
Revista: | Journal of Biomedical Materials Research: Part A |
Resumo(s): | This work reports on the influence of the substrate polarization of electroactive β-PVDF on human adipose stem cells (hASCs) differentiation under static and dynamic conditions. hASCs were cultured on different β-PVDF surfaces (non-poled and “poled -”) adsorbed with fibronectin and osteogenic differentiation was determined using a quantitative alkaline phosphatase assay. “Poled -” β-PVDF samples promote higher osteogenic differentiation, which is even higher under dynamic conditions. It is thus demonstrated that electroactive membranes can provide the necessary electromechanical stimuli for the differentiation of specific cells and therefore will support the design of suitable tissue engineering strategies, such as bone tissue engineering. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/38869 |
DOI: | 10.1002/jbm.a.35368 |
ISSN: | 1549-3296 1552-4965 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDF - FCD - Artigos/Papers (with refereeing) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Ribeiro_II_2015.pdf | 529,89 kB | Adobe PDF | Ver/Abrir |