Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/38393

Registo completo
Campo DCValorIdioma
dc.contributor.authorMendes, T.por
dc.contributor.authorKluskens, Leonpor
dc.contributor.authorRodrigues, L. R.por
dc.date.accessioned2015-11-24T16:08:47Z-
dc.date.available2015-11-24T16:08:47Z-
dc.date.issued2015-11-
dc.identifier.citationMendes, T.; Kluskens, Leon; Rodrigues, L. R., Triple negative breast cancer: nanosolutions for a big challenge. Advanced Science, 2(11), 1-14, 2015por
dc.identifier.issn2198-3844por
dc.identifier.urihttps://hdl.handle.net/1822/38393-
dc.description.abstractTriple negative breast cancer (TNBC) is a particular immunopathological subtype of breast cancer that lacks expression of estrogen and progesterone receptors (ER/PR) and amplification of the human epidermal growth factor receptor 2 (HER2) gene. Characterized by aggressive and metastatic phenotypes and high rates of relapse, TNBC is the only breast cancer subgroup still lacking effective therapeutic options, thus presenting the worst prognosis. The development of targeted therapies, as well as early diagnosis methods, is vital to ensure an adequate and timely therapeutic intervention in patients with TNBC. This review intends to discuss potentially emerging approaches for the diagnosis and treatment of TNBC patients, with a special focus on nano-based solutions that actively target these particular tumors.por
dc.description.sponsorshiphis study was supported by the Portuguese Foundation for Science and Technology (FCT) and the European Community fund FEDER, through Program COMPETE, under the scope of the Projects FCOMP01–0124-FEDER -0 21053 (PTDC/ SAU-BMA/121028/2010), PEst-OE/ EQB/LA0023/2013, RECI/BBB-EBI/0179/2012 (FCOMP-01–0124FEDER-027462), the strategic funding of UID/BIO/04469/2013 unit, and the Projects “BioHealth – Biotechnology and Bioengineering approaches to improve health quality”, REF. NORTE-07–0124-FEDER-000027, and “BioInd – Biotechnology and Bioengineering for improved Industrial and Agro-Food processes”, REF. NORTE-07–0124-FEDER-000028, co-funded by the Programa Operacional Regional do Norte (ON.2 – O Novo Norte), QREN, FEDER. Tânia Mendes acknowledges the FCT for supporting her PhD grant (SFRH / BD / 51955 / 2012).por
dc.language.isoengpor
dc.publisherWiley-VCH Verlagpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/121028/PTpor
dc.relationinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/132966/PTpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/126270/PTpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147337/PTpor
dc.rightsopenAccesspor
dc.subjectnanotechnologypor
dc.subjectdrug deliverypor
dc.subjectdiagnosticspor
dc.subjectcancer therapypor
dc.subjecttriple negative breast cancer (TNBC)por
dc.titleTriple negative breast cancer: nanosolutions for a big challengepor
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2198-3844por
dc.commentsCEB22162por
sdum.publicationstatuspublishedpor
oaire.citationStartPage1por
oaire.citationEndPage14por
oaire.citationIssue11por
oaire.citationTitleAdvanced Sciencepor
oaire.citationVolume2por
dc.date.updated2015-11-18T09:04:03Z-
dc.identifier.eissn2198-3844-
dc.identifier.doi10.1002/advs.201500053por
dc.subject.wosScience & Technologypor
sdum.journalAdvanced Sciencepor
Aparece nas coleções:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
document_22162_1.pdf610,92 kBAdobe PDFVer/Abrir

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID