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TitleFunctional chitosan microcarriers for selective cell attachment and expansion
Author(s)Custódio, Catarina Almeida
Cerqueira, M. T.
Marques, A. P.
Reis, R. L.
Mano, J. F.
KeywordsCell expansion
Cell separation
Issue dateJun-2014
JournalJournal of Tissue Engineering and Regenerative Medicine
CitationCustódio C. A., Cerqueira M. T., Marques A. P., Reis R. L., Mano J. F. Functional chitosan microcarriers for selective cell attachment and expansion, Termis EU 2014 , 2014
Abstract(s)The success of many stem cell applications in the biomedical field is highly dependent on the development of reliable techniques either for isolation or selection of specific cell populations with a very high yield and purity.1 In this work we propose the use of chitosan microparticles (μPs) to capture a specific cell type based in the concept of antibody-antigen binding. Our goal was to create new biomaterials capable of selecting within a heterotypic cell suspension, a specific sub-population, and supporting subsequent cell expansion. Such system simultaneously allows the selection and acts as a microcarrier for a specific target, thus reducing cell manipulation and time-consumption.
AccessOpen access
Appears in Collections:3B’s - Resumos em livros de atas de conferências - indexados no ISI Web of Science

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