Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/32906
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Oliveira, Mariana B. | por |
dc.contributor.author | Mano, J. F. | por |
dc.date.accessioned | 2015-01-15T15:48:04Z | - |
dc.date.available | 2015-01-15T15:48:04Z | - |
dc.date.issued | 2014-10 | - |
dc.date.submitted | 2014-10 | - |
dc.identifier.citation | Oliveira M. B., Mano J. F. High-throughput screening for integrative biomaterials design: exploring advances and new trends, Trends in Biotechnology, Vol. 32, Issue 12, pp. 627-636, doi:10.1016/j.tibtech.2014.09.009, 2014 | por |
dc.identifier.issn | 0167-7799 | por |
dc.identifier.uri | https://hdl.handle.net/1822/32906 | - |
dc.description.abstract | With the increasing need for biomaterials and tissue engineering alternatives, more accurate, rapid, and cost-saving methods and models to study biomaterial-cell interactions must be developed. We review the evolution of microarray platforms used for such studies in order to meet the criteria of complex tissue engineering biological environments. Particular aspects regarding biomaterials processing, data acquisition, and treatment are addressed. Apart from in vitroarray-based strategies, we also address emerging in vivo high-throughput approaches and their associated trends, such as the role of inflammation in regeneration. The up-scaling of high-throughput methods using single cell encapsulation systems is also explored. Possible limitations related to the use of such methods, such as spot-to-spot crosstalk, are also discussed. | por |
dc.description.sponsorship | Mariana B. Oliveira acknowledges the Fundacao para a Ciencia e a Tecnologia (FCT) for PhD grant SFRH/BD/71396/2010, Fundo Europeu de Desenvolvimento Regional (FEDER) through the Competitive Factors Operation Program Programa Operacional Factores de Competitividade (COMPETE) and national funds from the FCT in the scope of the project PTDC/CTM-BIO/1814/2012. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.rights | restrictedAccess | por |
dc.subject | Biomaterials | por |
dc.subject | High-throughput screening | por |
dc.subject | high-throughput | por |
dc.subject | combinatorial | por |
dc.subject | lab-on-chip testing | por |
dc.subject | arrays | por |
dc.title | High-throughput screening for integrative biomaterials design: exploring advances and new trends | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.cell.com/trends/biotechnology/abstract/S0167-7799(14)00191-7 | por |
dc.comments | http://www.3bs.uminho.pt/node/18136 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 627 | por |
oaire.citationEndPage | 636 | por |
oaire.citationIssue | 12 | por |
oaire.citationTitle | Trends in Biotechnology | por |
oaire.citationVolume | 32 | por |
dc.date.updated | 2015-01-15T14:40:23Z | - |
dc.identifier.doi | 10.1016/j.tibtech.2014.09.009 | por |
dc.identifier.pmid | 25450043 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Trends in Biotechnology | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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18136-Oliveiraetal_TrendsBiotech_2014.pdf Acesso restrito! | 735,26 kB | Adobe PDF | Ver/Abrir |