Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/31818
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Silva, Dina M. | por |
dc.contributor.author | Nunes, Cláudia | por |
dc.contributor.author | Pereira, Isabel Sofia Melo | por |
dc.contributor.author | Moreira, Ana S. P. | por |
dc.contributor.author | Domingues, M. R. M. | por |
dc.contributor.author | Coimbra, Manuel A. | por |
dc.contributor.author | Gama, F. M. | por |
dc.date.accessioned | 2014-12-10T16:41:19Z | - |
dc.date.available | 2014-12-10T16:41:19Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0144-8617 | por |
dc.identifier.uri | https://hdl.handle.net/1822/31818 | - |
dc.description.abstract | The characterization of several commercial dextrins and the analysis of the potential of dextrin derived hydrogels for biomedical applications were performed in this work. The structural characterization of dextrins allowed the determination of the polymerization and branching degrees, which ranged from 6 to 17 glucose residues and 2 to 13%, respectively. Tackidex, a medical grade dextrin was choosen for further characterization. The combination of hydrogel with a dextrin nanogel and urinary bladder matrix was achieved without compromising the mechanical properties or microstructure. The encapsulation of cells, preserving its viability, confirms the biocompatibility of the injectable hydrogels, which have therefore great potential for biomedical applications. | por |
dc.description.sponsorship | D.M.S. was supported by the grant SFRH/BD/64571/2009 from Fundacao para a Ciencia e Tecnologia (FCT), Portugal. We thank FCT funding through EuroNanoMed ENMED/0002/2010. The authors acknowledge the funding from QREN ("Quadro de Referencia Estrategica Nacional") and ADI ("Agencia de Inovacao") through the project Norte-07-0202-FEDER-038853.QOPNA research unit is funded by Fundacao para a Ciencia e a Tecnologia (FCT, Portugal, European Union, QREN, FEDER, and COMPETE (project PEst-C/QUI/UI0062/2013; FCOMP-01-0124-FEDER-037296), and the Portuguese National Mass Spectrometry Network, and Project PTDC/QUI-QUI/100044/2008. Ana S. P. Moreira and Claudia Nunes thanks FCT the grants (SFRH/BD/80553/2011; SFRH/BPD/46584/2008). The authors thank Prof. Dmitry V. Evtuguin for the use of SEC equipment. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.rights | openAccess | por |
dc.subject | Dextrin | por |
dc.subject | Injectable hydrogels | por |
dc.subject | Structural analysis | por |
dc.subject | MALDI-MS | por |
dc.subject | SEC | por |
dc.subject | MALDI-MS SEC | por |
dc.title | Structural analysis of dextrins and characterization of dextrin-based biomedical hydrogels | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.journals.elsevier.com/carbohydrate-polymers/ | por |
dc.comments | CEB18028 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 458 | por |
oaire.citationEndPage | 466 | por |
oaire.citationConferencePlace | United Kingdom | - |
oaire.citationTitle | Carbohydrate polymers | por |
oaire.citationVolume | 114 | por |
dc.date.updated | 2014-11-28T17:47:01Z | - |
dc.identifier.eissn | 0144-8617 | - |
dc.identifier.doi | 10.1016/j.carbpol.2014.08.009 | por |
dc.identifier.pmid | 25263914 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Carbohydrate polymers | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
document_18028_1.pdf | 1,31 MB | Adobe PDF | Ver/Abrir |