Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/31671

TitleThe use of bacteriophages for P. aeruginosa biofilm control
Author(s)Pires, Diana
Sillankorva, Sanna
Azeredo, Joana
KeywordsAdhesion
Biomechanics
Cellular biophysics
Drugs
Isolation technology
Microorganisms
Pseudomonas aeruginosa
Adherence
Bacteriophages
Bacterium
Biofilm control
Human epithelium
Isolation
Low antibiotic susceptibility
Lytic phages
Multidrug resistant strains
Nosocomial infections
Opportunistic pathogen
Planktonic cells
Virulence factors
Virulent biofllms
Antibiotics
Biomedical optical imaging
Hospitals
Immune system
Microorganisms
Optical buffering
Strain
Bacteriophages
Biofilms
Control
P. aeruginosa
Issue date2011
CitationPires, Diana; Sillankorva, Sanna; Azeredo, Joana, The use of bacteriophages for P. aeruginosa biofilm control. ENBENG 2011 - 1st Portuguese Meeting in Bioengineering. Lisbon, Portugal, 1-4 March, 1-42011. . ISBN: 978-1-4577-0522-9
Abstract(s)Pseudomonas aeruginosa is a relevant opportunistic pathogen frequently associated with several nosocomial infections and, worryingly, this bacterium shows a low antibiotic susceptibility. One of its virulence factors is related with the ability to adhere to surfaces and also human epithelium and form virulent biofllms. This work describes the isolation and characterization of lytic phages capable to infect antibiotic resistant P. aeruginosa strains. It is also described herein the potential of the new isolated phages for planktonic cells and biofilm control. According to the results of this work, the isolated phages showed different spectra of activity and most of them were efficient even against P. aeruginosa multidrug resistant strains. Furthermore, the biofilm infection assays revealed that phages can be a good strategy to combat virulent biofilms achieving significant reductions in the number of biofilm cells.
TypeConference paper
URIhttp://hdl.handle.net/1822/31671
ISBN978-1-4577-0522-9
DOI10.1109/ENBENG.2011.6026045
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Artigos em Livros de Atas / Papers in Proceedings

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