Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/30234

TitleTissue engineering and regenerative medicine: past, present, and future
Author(s)Salgado, A. J.
Oliveira, J. M.
Matins, A.
Teixeira, F. G.
Silva, N. A.
Neves, N. M.
Reis, R. L.
Sousa, Nuno
KeywordsRegenerative medicine
Tissue engineering
Biomaterials
Bone
Cartilage
Peripheral nerve
Scaffolds
Spinal cord
Stem cells
Issue dateOct-2013
PublisherElsevier
JournalInternational Review of Neurobiology
Abstract(s)Tissue and organ repair still represents a clinical challenge. Tissue engineering and regenerative medicine (TERM) is an emerging field focused on the development of alternative therapies for tissue/organ repair. This highly multidisciplinary field, in which bioengineering and medicine merge, is based on integrative approaches using scaffolds, cell populations from different sources, growth factors, nanomedicine, gene therapy, and other techniques to overcome the limitations that currently exist in the clinics. Indeed, its overall objective is to induce the formation of new functional tissues, rather than just implanting spare parts. This chapter aims at introducing the reader to the concepts and techniques of TERM. It begins by explaining how TERM have evolved and merged into TERM, followed by a short overview of some of its key aspects such as the combinations of scaffolds with cells and nanomedicine, scaffold processing, and new paradigms of the use of stem cells for tissue repair/regeneration, which ultimately could represent the future of new therapeutic approaches specifically aimed at clinical applications.
TypeBook part
URIhttp://hdl.handle.net/1822/30234
ISBN9780124104990
DOI10.1016/B978-0-12-410499-0.00001-0
ISSN0074-7742
Publisher versionhttp://www.sciencedirect.com/science/article/pii/B9780124104990000010
Peer-Reviewedyes
AccessRestricted access (UMinho)
Appears in Collections:3B’s - Capítulos de Livros/Book Chapters

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