Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/28584
Título: | Protein micro- and nano-capsules for biomedical applications |
Autor(es): | Shimanovich, Ulyana Bernardes, Gonçalo J. L. Knowles, T. P. J. Paulo, Artur Cavaco |
Data: | 2014 |
Editora: | Royal Society of Chemistry |
Revista: | Chemical Society Reviews |
Citação: | Chemical Society Reviews, 43(5), 1361-1371, 2014 |
Resumo(s): | Micro- and nano-scale systems have emerged as important tools for developing clinically useful drug delivery systems. In this tutorial review, we discuss the exploitation of biomacromolecules for this purpose, focusing on proteins, polypeptides, nucleic acids and polysaccharides and mixtures thereof as potential building blocks for novel drug delivery systems. We focus on the mechanisms of formation of micro- and nano-scale protein-based capsules and shells, as well as on the functionalization of such structures for use in targeted delivery of bioactive materials. We summarise existing methods for protein-based capsule synthesis and functionalization and highlight future challenges and opportunities for delivery strategies based on biomacromolecules. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/28584 |
DOI: | 10.1039/C3CS60376H |
ISSN: | 0306-0012 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2013 Protein micro- and nano-capsules for biomedical applications.pdf | Protein micro- and nano-capsules for biomedical applications | 1,68 MB | Adobe PDF | Ver/Abrir |