Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/25459
Título: | Cistus ladanifer as a source of phenolic compounds with antifungal activity |
Autor(es): | Barros, Lillian Duenas, M. Alves, Carlos Silva, Sónia Carina Henriques, Mariana Santos-Buelga, Celestino Ferreira, Isabel C. F. R. |
Data: | 2012 |
Editora: | Georg Thieme Verlag |
Revista: | Planta Medica |
Resumo(s): | A screening of the antifungal potential of phenolic extract of Cistus ladanifer from Northeast Portugal, against Candida species was performed. The extract was characterized by HPLC-DAD-ESI/MS. Phenolic acids and derivatives, ellagic acid derivatives and flavonoids, such as catechins, flavonols and flavones, were found in the sample, The most abudant group was ellagic acid derivatives in which punicalagin gallate, a derivative of punicalagin attached to gallic acid, was found in highest amount. These compounds could be related to the strong inhibition of C. albicans, C. glabrata and C. parapsilosis growth. Moreover, the best antifungal activity was against C. glabrata, where the studied extract was able to cause at least 3 Log of reduction at concentrations below 50μg/mL and a total growth inhibition at concentrations above 625 μg/mL. |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/25459 |
ISSN: | 1439-0221 |
e-ISSN: | 0032-0943 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Planta Medica.pdf | 411,79 kB | Adobe PDF | Ver/Abrir |