Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/24554
Título: | In vitro induction of melanin synthesis and extrusion by tamoxifen |
Autor(es): | Matamá, Maria Teresa Araújo, Rita Preto, Ana Paulo, Artur Cavaco Gomes, Andreia C |
Palavras-chave: | Catalase Cell culture Skin pigmentation SERM Genetic analysis Colour cosmetics |
Data: | Mai-2013 |
Editora: | Wiley |
Revista: | International Journal of Cosmetic Science |
Resumo(s): | Physical appearance has significant importance psychologically and socially, with skin and hair being of prime relevance. Effective ingredients that modulate melanin synthesis are of growing interest. Tamoxifen, a widely used selective oestrogen receptor modulator, SERM, was described occasionally in medical case reports as causing grey hair repigmentation. This work aimed to study, in vitro, the effect of tamoxifen and 4-hydroxy-tamoxifen, one of its most bioactive derivatives, on melanin production in human melanocytes. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/24554 |
DOI: | 10.1111/ics.12052 |
ISSN: | 0142-5463 |
Versão da editora: | http://dx.doi.org/10.1111/ics.12052 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series CBMA - Artigos/Papers DBio - Artigos/Papers |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2013 In vitro induction of melanin synthesis and extrusion by tamoxifen.pdf | In vitro induction of melanin synthesis and extrusion by tamoxifen | 421,07 kB | Adobe PDF | Ver/Abrir |