Bioactivity and viscoelastic characterization of chitosan/ bioglass® composite membranes

doi:10.1002/mabi.201200036

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/22753

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Campo DC	Valor	Idioma
dc.contributor.author	Caridade, S. G.	-
dc.contributor.author	Merino, Esther G.	-
dc.contributor.author	Alves, N. M.	-
dc.contributor.author	Mano, J. F.	-
dc.date.accessioned	2013-01-21T15:50:00Z	-
dc.date.available	2013-01-21T15:50:00Z	-
dc.date.issued	2012	-
dc.date.submitted	2012	-
dc.identifier.issn	1616-5187	por
dc.identifier.uri	https://hdl.handle.net/1822/22753	-
dc.description.abstract	Membranes of chitosan (CTS) and composite membranes of CTS with bioglass are prepared by solvent casting. The composite membranes are shown to induce the precipitation of apatite upon immersion in SBF. The biomineralization process is followed by measuring the variation of the viscoelastic properties of the membranes immersed in SBF, both online and offline. Nonconventional DMA is used to measure the change in the storage modulus, E0, and the loss factor, tan d, as a function of the immersion in SBF. A simple model is used to estimate the E0 of the apatite layer formed in vitro that is about 130 MPa. This work shows that innovate mechanical tests can be useful to characterize the mechanical performance of composites under physiological conditions.	por
dc.description.sponsorship	This work was financially supported by Foundation for Science and Technology (FCT) by the projects PTDC/QUI/69263/2006, PTDC/CTM-BPC/112774/2009 and, through the scholarship SFRH/BD/64601/2009 granted to Sofia G. Caridade.	por
dc.language.iso	eng	por
dc.publisher	Wiley	por
dc.rights	restrictedAccess	por
dc.subject	biomaterials	por
dc.subject	composites	por
dc.subject	guided tissue regeneration	por
dc.subject	hydroxyapatite	por
dc.subject	tissue engineering	por
dc.title	Bioactivity and viscoelastic characterization of chitosan/ bioglass® composite membranes	por
dc.type	article	por
dc.peerreviewed	yes	por
sdum.publicationstatus	published	por
oaire.citationStartPage	1106	por
oaire.citationEndPage	1113	por
oaire.citationIssue	8	por
oaire.citationTitle	Macromolecular Bioscience	por
oaire.citationVolume	12	por
dc.publisher.uri	John Wiley & Sons Ltd.	por
dc.identifier.eissn	1616-5195	por
dc.identifier.doi	10.1002/mabi.201200036	por
dc.identifier.pmid	22707301	por
dc.subject.wos	Science & Technology	por
sdum.journal	Macromolecular Bioscience	por
Aparece nas coleções:	3B’s - Artigos em revistas/Papers in scientific journals