Please use this identifier to cite or link to this item:

TitleHighly diastereoselective synthesis of aza-diels-alder reaction of danishefsky diene wiht glyoxylate imines
Author(s)Goth, Albertino João Brito
Alves, M. José
Rodríguez-Borges, José E.
Issue date2012
PublisherSociedade Portuguesa de Química (SPQ)
Abstract(s)Aza-Diels-Alder reaction is an exceptionally powerful synthetic method for the construction of six-membered nitrogen-heterocycles.[1-3] The reaction of Danishefsky's diene 1 with iminoacetates 2 (imines of glyoxylates) provides a convenient protocol for the synthesis of pipiridone adducts 3 (Scheme 1). In this context, we have performed the synthesis of various cycloadducts, precursors of a wide variety of chiral piperidines with potential use as non-natural amino acids or as precursors of biologically active compounds, including iminosugars (glycomimetics).
AccessOpen access
Appears in Collections:CDQuim - Comunicações e Proceedings

Files in This Item:
File Description SizeFormat 
Albertino_6SPJOCS_EB.pdfResumo102,99 kBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID