Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/1841
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Alves, M. José | - |
dc.contributor.author | Durães, M. Miguel | - |
dc.contributor.author | Fortes, A. Gil | - |
dc.date.accessioned | 2005-05-30T12:53:42Z | - |
dc.date.available | 2005-05-30T12:53:42Z | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | "Tetrahedron". 60 (2004) 6541-6553. | eng |
dc.identifier.issn | 0040-4020 | por |
dc.identifier.uri | https://hdl.handle.net/1822/1841 | - |
dc.description.abstract | A number of fused 4-oxo-1,3-diazabicyclo[4.1.0]heptane-6-carboxylates, a new type of compound, have been obtained by Diels-Alder cycloaddition between nucleophilic 2-azadienes and an electrophilic 2H-azirine. The reactions are completely endo- and regioselective, the azirine being added by its less hindered face to the diene. There are two isomers 7 and 8 formed from dienes 1 due either to isomerization of the cycloadducts 7 and 8 or by isomerization of the C=N bond of the diene during the reaction. The isomer 10 is formed from diene 2e, and a single diastereoisomer structure 4a-i is formed from dienes 11. Some pyrimidones 8a,7c/8c, 7e, 10, 11d have been hydrolyzed leading to functionalised aziridines 12, 13 and 15. | eng |
dc.description.sponsorship | Fundação para a Ciência e Tecnologia - POCTI/32723/QUI/2000. FEDER. | por |
dc.language.iso | eng | eng |
dc.publisher | Elsevier 1 | eng |
dc.rights | openAccess | eng |
dc.subject | 2-azadienes | eng |
dc.subject | 2H-azirines | eng |
dc.subject | Diels-alder cycloaddition | eng |
dc.title | Diels-alder cycloaddition of 2-azadienes to methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate in the synthesis of methyl 4-oxo-1,3-diazabicyclo[4.1.0]heptane-6-carboxylates | eng |
dc.type | article | eng |
dc.peerreviewed | yes | eng |
oaire.citationStartPage | 6541 | por |
oaire.citationEndPage | 6553 | por |
oaire.citationIssue | 31 | por |
oaire.citationVolume | 60 | por |
dc.identifier.doi | 10.1016/j.tet.2004.06.004 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Tetrahedron | por |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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MigFullPaperV2.pdf | 166,17 kB | Adobe PDF | Ver/Abrir |