Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/14753

TitleWound dressings for a proteolytic-rich environment
Author(s)Vasconcelos, Andreia
Paulo, Artur Cavaco
KeywordsWound healing
Silk fibroin
Collagen
Elastin
Keratin
Issue date2011
PublisherSpringer
JournalApplied Microbiology and Biotechnology
Abstract(s)Wound dressings have experienced continuous and significant changes over the years based on the knowledge of the biochemical events associated with chronic wounds. The development goes from natural materials used to just cover and conceal the wound to interactive materials that can facilitate the healing process, addressing specific issues in non-healing wounds. These new types of dressings often relate with the proteolytic wound environment and the bacteria load to enhance the healing. Recently, the wound dressing research is focusing on the replacement of synthetic polymers by natural protein materials to delivery bioactive agents to the wounds. This article provides an overview on the novel protein-based wound dressings such as silk fibroin keratin and elastin. The improved properties of these dressings, like the release of antibiotics and growth factors, are discussed. The different types of wounds and the effective parameters of healing process will be reviewed.
TypeArticle
URIhttp://hdl.handle.net/1822/14753
DOI10.1007/s00253-011-3135-4
ISSN0175-7598
Peer-Reviewedyes
AccessOpen access
Appears in Collections:DET/2C2T - Artigos em revistas internacionais com arbitragem científica

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