Please use this identifier to cite or link to this item:
|Title:||Enzymatic synthesis of Tinuvin|
Rodríguez Couto, S.
Paulo, Artur Cavaco
Guebitz, G. M.
|Journal:||Enzyme and Microbial Technology|
|Abstract(s):||Coupling of 3-(3-tert-butyl-4-hydroxyphenyl) propionic acid methylester to 1H-benzotriazole using a laccase from Trametes hirsuta was studied. The potentially resulting coupling product Tinuvin 1130 is an important UV-absorber used in polymer based materials. Oxidation of the phenol by the laccase led to homomolecular coupling reactions while the laccase did not attack 1H-benzotriazole. Due to the homomolecular reaction of the phenol in the presence of laccase coupling of phenol and 1H-benzotriazole was only observed when 1H-benzotriazole was applied in four-fold molar excess. The reaction was monitored by UV/vis spectroscopy, TLC and MS (ion trap) analysis. Coupling of 1H-benzotriazole took place in ortho position according to the postulated mechanism.|
|Appears in Collections:||DET/2C2T - Artigos em revistas internacionais com arbitragem científica|
Files in This Item:
|ENZYMATIC SYNTHESIS OF TINUVIN.pdf||Enzymatic synthesis of Tinuvin||332,43 kB||Adobe PDF||View/Open|