Nanotechnology and nature-sourced ingredients for tackling neurodegenerative diseases

Abstract

Neurodegenerative diseases (NDDs) pose a significant and pressing societal challenge in the twenty-first century, demanding immediate attention. Innovative approaches are actively being explored in the quest for more effective NDDs therapies. The pipeline of potential medicines offers hope, encompassing disease-modifying drugs, symptomatic treatments, and regenerative strategies. In parallel, natural products derived from plants are being investigated for their potential in alleviating associated symptoms but also impacting disease progression. The green synthesis of metal nanoparticles (MNPs) through environmentally friendly processes instigated the researchers to apply them in NDDs. This approach to synthesis of MNPs combines the best of both worlds, nanotechnology and natural products. Bio-inspired fabrication of MNPs proves distinct advantages over traditional methods, including scalability, low cost, and waste reduction. This chapter gives an overview of current challenges in NDDs management, current therapeutic options, and innovative strategies being developed, with a focus on nature-based solutions.