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https://hdl.handle.net/1822/87176
Título: | Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment |
Autor(es): | Bertão, Ana Raquel Ivasiv, Viktoriya Almeida Aguiar, Cristina Correia, Patrícia R. Fonseca, António M. Bañobre-López, Manuel Baltazar, Fátima Neves, Isabel C. |
Palavras-chave: | Zeolite 5-Fluorouracil Silver Microbial infections Tumor microenvironment |
Data: | 15-Jan-2024 |
Editora: | Elsevier 1 |
Revista: | Microporous and Mesoporous Materials |
Citação: | Bertão, A. R., Ivasiv, V., Almeida-Aguiar, C., Correia, P. R., Fonseca, A. M., Bañobre-López, M., … Neves, I. C. (2024, January). Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment. Microporous and Mesoporous Materials. Elsevier BV. http://doi.org/10.1016/j.micromeso.2023.112871 |
Resumo(s): | Several zeolite-based delivery systems (ZDS) built with faujasite structure were prepared containing silver (Ag+) and 5-Fluorouracil (5-FU) as antimicrobial and antineoplastic agents, respectively. The idea behind this drug combination is an answer to the increasing evidence of colonization of tumor microenvironments by pathogenic microorganisms and their active role in tumor growth. Two ZDS with a fixed load of 5-FU and different silver loads, Ag7(5-FU). |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/87176 |
DOI: | 10.1016/j.micromeso.2023.112871 |
ISSN: | 1387-1811 |
Versão da editora: | https://www.sciencedirect.com/science/article/pii/S138718112300447X |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series CBMA - Artigos/Papers CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_56494_1.pdf | 2,05 MB | Adobe PDF | Ver/Abrir |