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https://hdl.handle.net/1822/85566
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Campo DC | Valor | Idioma |
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dc.contributor.author | Albuquerque, Priscilla B. S. | por |
dc.contributor.author | de Souza, M. P. | por |
dc.contributor.author | Bourbon, Ana I. | por |
dc.contributor.author | Cerqueira, Miguel A. | por |
dc.contributor.author | Pastrana, L. | por |
dc.contributor.author | Jauregi, P. | por |
dc.contributor.author | Teixeira, J. A. | por |
dc.contributor.author | Carneiro-da-Cunha, M. das Graças | por |
dc.date.accessioned | 2023-07-19T08:34:42Z | - |
dc.date.available | 2023-07-19T08:34:42Z | - |
dc.date.issued | 2023-05-31 | - |
dc.identifier.citation | Albuquerque, Priscilla B. S.; de Souza, M. P.; Bourbon, Ana I.; Cerqueira, Miguel A.; Pastrana, L.; Jauregi, P.; Teixeira, José A.; Carneiro-da-Cunha, M. das Graças, Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films. Applied Nano, 4(2), 159-177, 2023 | por |
dc.identifier.issn | 2673-3501 | por |
dc.identifier.uri | https://hdl.handle.net/1822/85566 | - |
dc.description | Data Availability Statement: Data supporting reported results of this work are contained within the article. The data presented in this study are available in the following articles: “Cross-linked chi- tosan/liposome hybrid system for the intestinal delivery of quercetin”, “Immobilization of bioactive compounds in Cassia grandis galactomannan-based films: Influence on physicochemical properties”, “Delonix regia galactomannan-based edible films: Effect of molecular weight and k-carrageenan on physicochemical properties”, “Development of edible films prepared by soy protein and the galactomannan fraction extracted from Gleditsia triacanthos (Fabaceae) seed”, and “Preparation and characterization of konjac glucomannan-based bionanocomposite film for active food packaging”. | por |
dc.description.abstract | The objective of this work was to prepare different concentrations of liposomes based on lecithin containing quercetin, and evaluate their effect on the properties of galactomannan films obtained from Cassia grandis seeds. Quercetin-loaded lecithin liposomes (QT-LL) were obtained by the ethanol injection method by incorporating quercetin in different concentrations in a previously prepared suspension of lecithin liposomes in water. Following characterization of QT-LLs by zeta potential and dynamic light scattering, QT-LL with 75 µg quercetin/mL suspension was incorporated at different concentrations in galactomannan films. The films obtained were characterized for color, solubility, moisture content (MC), water vapor permeability (WVP), scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier-transform infrared (FTIR) spectroscopy. The size of lecithin liposomes with no quercetin was statistically than those containing quercetin above 50 µg/mL. All the QT-LLs presented a low polydispersity index, even considering their significant differences and similar values for zeta potential. The films displayed a rough surface and the galactomannan structure was confirmed by FTIR. Additionally, the amorphous nature of the polysaccharide was observed by XRD. The films were luminous, with a predominant yellow tendency and low opacity. The incorporation of QT-LL in galactomannan films did not lead to statistical differences for solubility and MC, while significant differences were observed for WVP. Galactomannan films were shown to be a promising structure for the incorporation of lecithin liposomes loaded with quercetin, pointing at promising applications for different applications. | por |
dc.description.sponsorship | This study was supported by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) and under the scope of the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462). P.A. receipted a scholarship from CAPES. M.d.G.C.-d.-C. express her gratitude to the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) for research grants and fellowship. The authors acknowledge CNPq and CAPES for financial support. | por |
dc.language.iso | eng | por |
dc.publisher | MDPI | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FBIO%2F04469%2F2013/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/RECI%2FBBB-EBI%2F0179%2F2012/PT | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | bioactive compounds | por |
dc.subject | biopolymers | por |
dc.subject | heath applications | por |
dc.subject | encapsulation | por |
dc.subject | polysaccharides | por |
dc.title | Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.mdpi.com/2673-3501/4/2/9 | por |
dc.comments | CEB56340 | por |
oaire.citationStartPage | 159 | por |
oaire.citationEndPage | 177 | por |
oaire.citationIssue | 2 | por |
oaire.citationVolume | 4 | por |
dc.date.updated | 2023-07-18T22:00:37Z | - |
dc.identifier.doi | 10.3390/applnano4020009 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
sdum.journal | Applied Nano | por |
oaire.version | VoR | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_56340_1.pdf | 3,33 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons