Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/80177
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Carneiro, Liliana | por |
dc.contributor.author | Pinto, Alexandra M. F. R. | por |
dc.contributor.author | Sales, M. G. F. | por |
dc.date.accessioned | 2022-10-17T11:07:09Z | - |
dc.date.available | 2022-10-17T11:07:09Z | - |
dc.date.issued | 2023-01-15 | - |
dc.identifier.citation | Carneiro, Liliana; Pinto, Alexandra M. F. R.; Sales, M. G. F., Development of an innovative flexible paper-based methanol fuel cell (PB-DMFC) sensing platform application to sarcosine detection. Chemical Engineering Journal, 452, Part 4(139563), 2023 | por |
dc.identifier.issn | 1385-8947 | por |
dc.identifier.uri | https://hdl.handle.net/1822/80177 | - |
dc.description.abstract | This work describes for the first time a paper-based direct methanol fuel cell platform (PB-DMFC) that functions as an energy source and biosensor, assembled on a simple paper substrate for point-of-care (POC) applications, targeting sarcosine as proof-of-concept. Specifically, a methanol fuel cell strip was developed from a square of Whatman paper, acting as substrate. The paper strip was treated with an impermeable agent (paraffin solution) and supported all fuel cell device components, including the electrolyte (Nafion®), anode electrode (carbon black Pt/Ru), cathode electrode (carbon black Pt), and current collectors (silver edges). All the described components formed a flexible single layer that operated in a completely passive mode by adding few microliters of a methanol solution on the anode side and by using atmospheric oxygen on the cathode side. The obtained platform had a stable electrical signal with an average OCV value of 0.45-0.55V and a maximum power density of 20-50µW/cm2, depending on the methanol concentration used (0.5M 2M). A sensing layer was built in situ on the anode electrode by electropolymerization of a solution of 3,4-ethylenedioxythiophene (EDOT) and pyrrole (Py) as monomers. The obtained PB-DMFC/biosensor was calibrated at room temperature in buffer and healthy human urine and showed linear responses from 1.0×10-7 to 1.0×10-3M with a detection limit of 6.6×10-8M. Selectivity studies evidenced signals changing within 1-10%, both in positive and negative directions. Results evidenced good reproducibility. Overall, the obtained results demonstrate a self-sufficient biosensor for the detection of sarcosine consisting of an innovative paper-based methanol fuel cell strip. This concept can open new horizons for massification of biosensors even in places with energy shortage. | por |
dc.description.sponsorship | The authors acknowledge the financial support of EU-Horizon 2020 (Symbiotic, FET-Open, GA665046) and LPTC (Grant references: SFRH/BD/122954/2016; COVID/BD/151738/2021) acknowledges Fundação para a Ciência e Tecnologia (FCT) for financial support. This work was also financially supported by LA/P/0045/2020 (ALiCE), UIDB/00532/2020 and UIDP/00532/2020 (CEFT), funded by national funds through FCT/MCTES (PIDDAC). | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/POR_NORTE/SFRH%2FBD%2F122954%2F2016/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/POR_NORTE/COVID%2FBD%2F151738%2F2021/PT | por |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/665046/EU | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00532%2F2020/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00532%2F2020/PT | por |
dc.rights | openAccess | por |
dc.subject | Paper-based methanol fuel cell | por |
dc.subject | Sensing platform | por |
dc.subject | Molecularly imprinted polymer | por |
dc.subject | Sarcosine | por |
dc.subject | Point of care | por |
dc.subject | Cancer biomarker | por |
dc.title | Development of an innovative flexible paper-based methanol fuel cell (PB-DMFC) sensing platform application to sarcosine detection | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1385894722050422 | por |
dc.comments | CEB55790 | por |
oaire.citationConferencePlace | Netherlands | - |
dc.date.updated | 2022-10-17T10:53:34Z | - |
dc.identifier.doi | 10.1016/j.cej.2022.139563 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
sdum.journal | Chemical Engineering Journal | por |
dc.identifier.articlenumber | 139563 | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55790_1.pdf | 3,85 MB | Adobe PDF | Ver/Abrir |