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https://hdl.handle.net/1822/74813
Título: | Orange thyme: phytochemical profiling, in vitro bioactivities of extracts and potential health benefits |
Autor(es): | Silva, Amélia M. Félix, Luís M. Teixeira, Isabel Martins-Gomes, Carlos Schäfer, Judith Souto, Eliana B. Santos, Dario J. Bunzel, Mirko Nunes, Fernando M. |
Palavras-chave: | Orange thyme Phenolic composition Antioxidant activity Anti-proliferative Anti-inflammatory activity Aqueous extract Hydroethanolic extract Radical scavenging activities Apigenin (PubChem CID: 5280443) Eriodictyol (Pubchem CID 440735) Luteolin (PubChem CID: 5280445) Rosmarinic acid (PubChem CID: 5281792) Salvianolic acid I (Pubchem CID 10459878) Salvianolic acid K (Pubchem CID 10482829) |
Data: | 30-Dez-2021 |
Editora: | Elsevier 1 |
Revista: | Food Chemistry: X |
Citação: | Silva, Amélia M.; Félix, Luís M.; Teixeira, Isabel; Martins-Gomes, Carlos; Schäfer, Judith; Souto, Eliana B.; Santos, Dario J.; Bunzel, Mirko; Nunes, Fernando M., Orange thyme: phytochemical profiling, in vitro bioactivities of extracts and potential health benefits. Food Chemistry: X, 12(100171), 2021 |
Resumo(s): | Orange thyme (Thymus fragrantissimus) is becoming widely used in food as a condiment and herbal tea, nevertheless its chemical composition and potential bioactivities are largely unknown. Thus the objective of this work is to obtain a detailed phytochemical profile of T. fragrantissimus by exhaustive ethanolic extraction and by aqueous decoction mimicking its consumption. Extracts showed high content in rosmarinic acid, luteolin-O-hexuronide and eriodictyol-O-hexuronide; these were the main phenolic compounds present in orange thyme accounting for 85% of the total phenolic compounds. Orange thyme extracts presented high scavenging activity against nitric oxide and superoxide radicals. Both extracts presented significant inhibitory effect of tyrosinase activity and moderate anti-acetylcholinesterase activity. Both extracts showed a good in vitro anti-inflammatory activity and a weak anti-proliferative/cytotoxic activity against Caco-2 and HepG2 cell lines supporting its safe use. Orange thyme is a very good source of bioactive compounds with potential use in different food and nutraceutical industries. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/74813 |
DOI: | 10.1016/j.fochx.2021.100171 |
ISSN: | 2590-1575 |
Versão da editora: | https://www.sciencedirect.com/journal/food-chemistry-x |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55025_1.pdf | 906,8 kB | Adobe PDF | Ver/Abrir |