Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/7467
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Abrunhosa, Luís | - |
dc.contributor.author | Costa, M. | - |
dc.contributor.author | Areias, F. | - |
dc.contributor.author | Venâncio, Armando | - |
dc.contributor.author | Proença, M. Fernanda R. P. | - |
dc.date.accessioned | 2008-01-10T20:14:40Z | - |
dc.date.available | 2008-01-10T20:14:40Z | - |
dc.date.issued | 2007-12 | - |
dc.date.submitted | 2007 | - |
dc.identifier.citation | L Abrunhosa, M Costa, F Areias, A Venâncio, F Proença, Antifungal activity of a novel chromene dimer, Journal of Industrial Microbiology and Biotechnology, Volume 34, Issue 12, 1 December 2007, Pages 787–792, https://doi.org/10.1007/s10295-007-0255-z | eng |
dc.identifier.issn | 1367-5435 | eng |
dc.identifier.uri | https://hdl.handle.net/1822/7467 | - |
dc.description.abstract | The activity on Aspergillus spp. growth and on ochratoxin A production of two novel chromene dimers (3) was evaluated. The results of the bioassays indicate that the chromene dimer 3a inhibited mycelia growth by approximately 50% (EC50) at 140.1 μmol L−1 for A. niger, 384.2 μmol L−1 for A. carbonarius, 69.1 μmol L−1 for A. alliaceus and 559.1 μmol L−1 for A. ochraceus. When applied at concentrations of 2 mmol L−1, 3a totally inhibited the growth of all Aspergillus spp. tested. Furthermore, ochratoxin A production by A. alliaceus was reduced by about 94% with a 200 μmol L−1 solution of this compound. A moderate inhibitory effect was observed for the analogous structure 3b on ochratoxin A production but not in mycelia growth. No inhibition was registered for compounds 2a and 2b, used as synthetic precursors of the dimeric species 3. | eng |
dc.description.sponsorship | Fundação para a Ciência e a Tecnologia (FCT) - SFRH/BD/11228/2002. | por |
dc.language.iso | eng | eng |
dc.publisher | Oxford University Press | eng |
dc.relation | info:eu-repo/grantAgreement/FCT/POCI-2010/SFRH%2FBD%2F11228%2F2002/PT | - |
dc.rights | openAccess | eng |
dc.subject | Chromenes | eng |
dc.subject | Aspergillus spp. | eng |
dc.subject | Ochratoxin A | eng |
dc.subject | Antifungal compounds | eng |
dc.title | Antifungal activity of a novel chromene dimer | eng |
dc.type | article | por |
dc.peerreviewed | yes | eng |
dc.relation.publisherversion | https://academic.oup.com/jimb/article/34/12/787/5993107 | - |
sdum.number | 12 | eng |
sdum.pagination | 787-792 | eng |
sdum.publicationstatus | published | eng |
sdum.volume | 34 | eng |
oaire.citationStartPage | 787 | por |
oaire.citationEndPage | 792 | por |
oaire.citationIssue | 12 | por |
oaire.citationVolume | 34 | por |
dc.identifier.eissn | 1476-5535 | - |
dc.identifier.doi | 10.1007/s10295-007-0255-z | por |
dc.identifier.pmid | 17899234 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Industrial Microbiology and Biotechnology | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Abrunhosa_etal_2007_JIMB.pdf | 488,26 kB | Adobe PDF | Ver/Abrir |