Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/70786
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Azeredo, Joana | por |
dc.contributor.author | García, Pilar | por |
dc.contributor.author | Drulis-Kawa, Zuzanna | por |
dc.date.accessioned | 2021-03-15T11:40:39Z | - |
dc.date.available | 2021-03-15T11:40:39Z | - |
dc.date.issued | 2021-04 | - |
dc.identifier.citation | Azeredo, Joana; García, Pilar; Drulis-Kawa, Zuzanna, Targeting biofilms using phages and their enzymes. Current Opinion in Biotechnology, 68, 251-261, 2021 | por |
dc.identifier.issn | 0958-1669 | por |
dc.identifier.uri | https://hdl.handle.net/1822/70786 | - |
dc.description | "Available online 10 March 2021" | por |
dc.description.abstract | The complex biofilm architecture composed of extracellular polymeric structures (EPS) provides a protective shield to physiologically diverse bacterial cells immersed in its structure. The evolutionary interplay between bacteria and their viruses (phages) forced the latter ones to develop specific strategies to overcome the biofilm defensive barriers and kill sessile cells. Phages are equipped with a wide panel of enzyme-degrading EPS macromolecules which together are powerful weapons to combat biofilms. Antibiofilm performance can be achieved by combining phages or phage-borne enzymes with other antimicrobials such as antibiotics. Nevertheless, a variety of enzymes encoded in phage genomes still need to be explored. To advance in biofilm control strategies we must deepen the understanding of the biofilm biology itself, as well as discover and better exploit the unlimited antibacterial potential of phages. | por |
dc.description.sponsorship | JA was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UIDB/04469/2020 unit. PG was supported by grants from Innovative Training Networks (ITN) Marie Skłodowska-Curie Actions H2020-MSCA-ITN2018. Reference 813439, and PID2019-105311RB-I00 (MICIU/AEI/FEDER, UE, Spain). ZDK was supported by the National Science Centre of Poland (Narodowe Centrum Nauki), grant numbers 2016/21/B/NZ6/01157 and 2017/26/M/NZ1/00233. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | UIDB/04469/2020 | por |
dc.rights | openAccess | por |
dc.title | Targeting biofilms using phages and their enzymes | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.journals.elsevier.com/current-opinion-in-biotechnology | por |
dc.comments | CEB54272 | por |
oaire.citationStartPage | 251 | por |
oaire.citationEndPage | 261 | por |
oaire.citationConferencePlace | Netherlands | - |
oaire.citationVolume | 68 | por |
dc.date.updated | 2021-03-13T14:03:10Z | - |
dc.identifier.eissn | 1879-0429 | por |
dc.identifier.doi | 10.1016/j.copbio.2021.02.002 | por |
dc.identifier.pmid | 33714050 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Current Opinion in Biotechnology | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
document_54272_1.pdf | 1,73 MB | Adobe PDF | Ver/Abrir |