Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/70496
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Fernandes, Liliana Sousa | por |
dc.contributor.author | Ribeiro, Henrique Gonçalves | por |
dc.contributor.author | Oliveira, Ana C. A. | por |
dc.contributor.author | Silva, Ana Sanches | por |
dc.contributor.author | Freitas, Andreia | por |
dc.contributor.author | Henriques, Mariana | por |
dc.contributor.author | Rodrigues, Maria Elisa Costa | por |
dc.date.accessioned | 2021-03-01T12:13:13Z | - |
dc.date.available | 2021-03-01T12:13:13Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Fernandes, L.; Ribeiro, Henrique G.; Oliveira, Ana C. A.; Silva, Ana Sanches; Freitas, Andreia; Henriques, Mariana; Rodrigues, M. Elisa, Portuguese honeys as antimicrobial agents against Candida species. Journal of Traditional and Complementary Medicine, 11(2), 130-136, 2021. | por |
dc.identifier.issn | 2225-4110 | por |
dc.identifier.uri | https://hdl.handle.net/1822/70496 | - |
dc.description.abstract | Background and aim Honey has been recognized worldwide for its antioxidant, anti-tumor, anti-inflammatory and antimicrobial properties. Among them, the antifungal properties associated to honey make it an attractive alternative treatment for Candida-associated infections, particularly for topical application to the mucous membranes and skin. In this sense, the main purpose of this work was to evaluate physicochemical properties of five Portuguese honeys and Manuka honey (an Australian honey with well recognized medical proprieties, used as control) and to evaluate the antifungal activity in Candida species planktonic and biofilm assays. Experimental procedure Pollen analysis, pH determination, color, concentration of protein and methylglyoxal, conductivity, total phenolics and flavonoids, hydrogen peroxide concentration, and characterization by differential scanning calorimetry in honey samples were determined. Additionally, the effect of honeys on planktonic growth of Candida was initially evaluated by determination of the minimum inhibitory concentrations. Then, the same effect of those honeys was evaluated in biofilms, by Colony Forming Units enumeration. Results and conclusion It has been shown that Portuguese heather (Erica cinereal) honey presented the most similar physicochemical properties to manuka honey (specially phenolic and flavonoids contents). The five Portuguese honeys under study, presented in general a potent activity against planktonic multi-resistant yeast pathogens (several clinical isolates and reference strains of Candida species) and S. aureus and P. aeruginosa bacteria cultures. Additionally, it was also concluded that Portuguese heather honey (50% and 75% (w/v)) can also act as a good Candida species biofilm reducer, namely for C. tropicalis. | por |
dc.description.sponsorship | This study was supported by the Portuguese Foundation for Science and Technology (FCT), Portugal, under the scope of the strategic funding of UIDBB/04469/2020020 unit and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund, Portugal, under the scope of Norte 2020 - Programa Operacional Regional do Norte. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | UIDBB/04469/2020020 | por |
dc.relation | NORTE-01-0145-FEDER-000004 | por |
dc.rights | openAccess | por |
dc.subject | Honey characterization | por |
dc.subject | Honey therapy | por |
dc.subject | Candida species | por |
dc.subject | Candida biofilm | por |
dc.subject | Natural antimicrobial approach | por |
dc.title | Portuguese honeys as antimicrobial agents against Candida species | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.journals.elsevier.com/journal-of-traditional-and-complementary-medicine | por |
dc.comments | CEB53598 | por |
oaire.citationStartPage | 130 | por |
oaire.citationEndPage | 136 | por |
oaire.citationIssue | 2 | por |
oaire.citationConferencePlace | India | - |
oaire.citationVolume | 11 | por |
dc.date.updated | 2021-03-01T09:33:46Z | - |
dc.identifier.doi | 10.1016/j.jtcme.2020.02.007 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Traditional and Complementary Medicine | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_53598_1.pdf | 599,08 kB | Adobe PDF | Ver/Abrir |