IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity

doi:10.1016/j.jaci.2017.02.034

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/67150

Título:	IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity
Autor(es):	Cunha, Cristina Gonçalves, Samuel M. Duarte-Oliveira, Claudio Leite, Luis Lagrou, Katrien Marques, António Lupianez, Carmen B. Mesquita, Inês Gaifem, Joana Barbosa, Ana Margarida Vaz, Carlos Pinho Branca, Rosa Campilho, Fernando Freitas, Fatima Ligeiro, Dario Lass-Floerl, Cornelia Loffler, Jurgen Jurado, Manuel Saraiva, Margarida Kurzai, Oliver Rodrigues, Fernando Castro, António G. Silvestre, Ricardo Sainz, Juan Maertens, Johan A. Torrado, Egídio Jacobsen, Ilse D. Lacerda, Joao F. Campos, Antonio, Jr. Carvalho, Agostinho
Palavras-chave:	Adult Aspergillosis Female Hematopoietic Stem Cell Transplantation Humans Interleukin-10 Leukocytes, Mononuclear Macrophages Male Polymorphism, Single Nucleotide Young Adult Genetic Predisposition to Disease
Data:	2017
Editora:	Mosby Inc.
Revista:	Journal of Allergy and Clinical Immunology
Resumo(s):	[Excerpt] To the Editor: Proinflammatory immune responses are critically required for antimicrobial host defenses; however, excessive inflammation has the potential to damage host tissues thereby paradoxically contributing to the progression of infection.[...]
Tipo:	Carta ao editor
URI:	https://hdl.handle.net/1822/67150
DOI:	10.1016/j.jaci.2017.02.034
ISSN:	0091-6749
e-ISSN:	1097-6825
Arbitragem científica:	yes
Acesso:	Acesso restrito UMinho
Aparece nas coleções:	ICVS - Artigos em revistas internacionais / Papers in international journals