Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/66856
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Zielinska, Aleksandra | por |
dc.contributor.author | Carreiró, Filipa | por |
dc.contributor.author | Oliveira, Ana M. | por |
dc.contributor.author | Neves, Andreia | por |
dc.contributor.author | Pires, Bárbara | por |
dc.contributor.author | Venkatesh, D. Nagasamy | por |
dc.contributor.author | Durazzo, Alessandra | por |
dc.contributor.author | Lucarini, Massimo | por |
dc.contributor.author | Eder, Piotr | por |
dc.contributor.author | Silva, Amélia M. | por |
dc.contributor.author | Santini, Antonello | por |
dc.contributor.author | Souto, Eliana B. | por |
dc.date.accessioned | 2020-09-08T14:56:53Z | - |
dc.date.available | 2020-09-08T14:56:53Z | - |
dc.date.issued | 2020-08-15 | - |
dc.identifier.citation | Zielinska, Aleksandra; Carreiró, Filipa; Oliveira, Ana M.; Neves, Andreia; Pires, Bárbara; Venkatesh, D. Nagasamy; Durazzo, Alessandra; Lucarini, Massimo; Eder, Piotr; Silva, Amélia M.; Santini, Antonello; Souto, Eliana, Polymeric nanoparticles: production, characterization, toxicology and ecotoxicology. Molecules, 25(16), 3731, 2020 | por |
dc.identifier.uri | https://hdl.handle.net/1822/66856 | - |
dc.description.abstract | Polymeric nanoparticles (NPs) are particles within the size range from 1 to 1000 nm and can be loaded with active compounds entrapped within or surface-adsorbed onto the polymeric core. The term “nanoparticle” stands for both nanocapsules and nanospheres, which are distinguished by the morphological structure. Polymeric NPs have shown great potential for targeted delivery of drugs for the treatment of several diseases. In this review, we discuss the most commonly used methods for the production and characterization of polymeric NPs, the association efficiency of the active compound to the polymeric core, and the in vitro release mechanisms. As the safety of nanoparticles is a high priority, we also discuss the toxicology and ecotoxicology of nanoparticles to humans and to the environment. | por |
dc.description.sponsorship | This research was supported by the Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) through the projects M-ERA-NET/0004/2015-PAIRED, UIDB/04469/2020 (strategic fund) and UIDB/04033/2020 (to CITAB), co-financed by FEDER, under the Partnership Agreement PT2020 | por |
dc.language.iso | eng | por |
dc.publisher | MDPI | por |
dc.relation | M-ERA-NET/0004/2015-PAIRED | por |
dc.relation | UIDB/04469/2020 | por |
dc.relation | UIDB/04033/2020 | por |
dc.rights | openAccess | por |
dc.subject | Polymeric nanoparticles | por |
dc.subject | Nanocapsules | por |
dc.subject | Nanospheres | por |
dc.subject | Therapeutic potential | por |
dc.subject | Targeted drug delivery | por |
dc.subject | Toxicology | por |
dc.subject | Ecotoxicology | por |
dc.title | Polymeric nanoparticles: production, characterization, toxicology and ecotoxicology | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.mdpi.com/journal/molecules | por |
dc.comments | CEB53860 | por |
oaire.citationIssue | 16 | por |
oaire.citationVolume | 25 | por |
dc.date.updated | 2020-08-22T20:09:03Z | - |
dc.identifier.eissn | 1420-3049 | por |
dc.identifier.doi | 10.3390/molecules25163731 | por |
dc.identifier.pmid | 32824172 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Molecules | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_53860_1.pdf | 1,56 MB | Adobe PDF | Ver/Abrir |