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https://hdl.handle.net/1822/62511
Título: | Implementation of a cervical cancer screening strategy using HPV self-sampling for women living in rural areas |
Autor(es): | Possati-Resende, Júlio Cesar Vazquez, Fabiana de Lima Pantano, Naitielle de Paula Fregnani, José Humberto Tavares Guerreiro Mauad, Edmundo Carvalho Longatto, Adhemar |
Palavras-chave: | Cervical cancer screening Cervix cancer Human papillomavirus Self-sampling Rural population |
Data: | 2020 |
Editora: | Karger Publishers |
Revista: | Acta Cytologica |
Citação: | Possati-Resende, J. C., de Lima Vazquez, F., de Paula Pantano, N., et. al. (2020). Implementation of a cervical cancer screening strategy using HPV self-sampling for women living in rural areas. Acta Cytologica, 64(1-2), 1-9. |
Resumo(s): | Background: The implementation of population screening for cervical lesions in rural areas has been particularly challenging for a variety of reasons, including geographic isolation, limited access to medical care, lack of awareness of cancer risks, lower education levels, and embarrassment about having the clinical examination. Methods: This study was designed to evaluate the use of self-sampling for human papillomavirus (HPV) screening in the rural communities served by our hospital. To develop the study group, we trained a local police officer who was already interacting with the rural community to explain cancer risks and the ease of self-sampling to the women. Results: We identified a study group of 386 women, of whom 369 (95.6%) agreed to participate in the study. To test for high-risk HPV, we performed the Cobas PCR test, and of 340 valid samples, 45 (12.2%) were positive for at least 1 of the high-risk HPV subtypes. All positively tested women were referred for colposcopy and Papanicolaou testing. The follow-up biopsies showed that 40% had low-grade intraepithelial neoplasia (CIN1), 6.6% had high-grade intraepithelial neoplasia (CIN2/3), and 4.4% had squamous cell carcinoma. Conclusions: Self-collection for HPV testing by women living in isolated communities is highly efficient and has potential for cost-effective screening by taking advantage of existing support networks, such as the local police service |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/62511 |
DOI: | 10.1159/000493333 |
ISSN: | 0001-5547 |
e-ISSN: | 1938-2650 |
Versão da editora: | https://www.karger.com/Article/Abstract/493333 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito autor |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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possati-resende2019.pdf Acesso restrito! | 529,92 kB | Adobe PDF | Ver/Abrir |