Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/62088
Título: | The dynamics of the stress neuromatrix |
Autor(es): | Sousa, Nuno |
Palavras-chave: | Animals Brain Humans Models, Neurological Stress, Psychological Brain Mapping |
Data: | Mar-2016 |
Editora: | Springer Nature |
Revista: | Molecular Psychiatry |
Citação: | Sousa, N. (2016). The dynamics of the stress neuromatrix. Molecular psychiatry, 21(3), 302. |
Resumo(s): | Stressful stimuli in healthy subjects trigger activation of a consistent and reproducible set of brain regions; yet, the notion that there is a single and constant stress neuromatrix is not sustainable. Indeed, after chronic stress exposure there is activation of many brain regions outside that network. This suggests that there is a distinction between the acute and the chronic stress neuromatrix. Herein, a new working model is proposed to understand the shift between these networks. The understanding of the factors that modulate these networks and their interplay will allow for a more comprehensive and holistic perspective of how the brain shifts 'back and forth' from a healthy to a stressed pattern and, ultimately, how the latter can be a trigger for several neurological and psychiatric conditions. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/62088 |
DOI: | 10.1038/mp.2015.196 |
ISSN: | 1359-4184 |
e-ISSN: | 1476-5578 |
Versão da editora: | https://www.nature.com/articles/mp2015196 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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mp2015196.pdf Acesso restrito! | 1,48 MB | Adobe PDF | Ver/Abrir |