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https://hdl.handle.net/1822/61598
Título: | Opinion on moderate/low cancer genetic risk markers in medical practice including comment on the article Genetic contribution to all cancers: the first demonstration using the model of breast cancers from Poland stratified by age at diagnosis and tumour pathology by Lubinski et al., Breast Cancer Res Treat 2008 Apr 15 |
Autor(es): | Costa, Sandra Schmitt, Fernando C. |
Data: | 15-Jun-2008 |
Editora: | BMC |
Revista: | Hereditary Cancer in Clinical Practice |
Resumo(s): | [Excerpt] Breast cancer is a heterogeneous disease characterized by a widely variable morphological appearance, many risk factors and distinct gene expression profiles [1, 2]. Common genetic alterations (e.g. polymorphisms), with possible effects on protein function and/or expression, within genes involved in essential cellular pathways, such as carcinogen metabolism, DNA repair, cell cycle control and cell proliferation, can predispose individuals to various tumours, including breast cancer [3-7]. [...] |
Tipo: | Editorial em revista |
URI: | https://hdl.handle.net/1822/61598 |
ISBN: | 1897-4287 |
DOI: | 10.1186/1897-4287-6-2-64 |
ISSN: | 1731-2302 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Costa-2008-Opinion-on-moderate-low-cancer-gene.pdf | 45,9 kB | Adobe PDF | Ver/Abrir |