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https://hdl.handle.net/1822/55757
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Campo DC | Valor | Idioma |
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dc.contributor.author | Silva, Hélder D. | por |
dc.contributor.author | Poejo, Joana | por |
dc.contributor.author | Pinheiro, Ana Cristina | por |
dc.contributor.author | Donsì, Francesco | por |
dc.contributor.author | Serra, Ana Teresa | por |
dc.contributor.author | Duarte, Catarina M. M. | por |
dc.contributor.author | Ferrari, Giovanna | por |
dc.contributor.author | Cerqueira, Miguel Ângelo Parente Ribeiro | por |
dc.contributor.author | Vicente, A. A. | por |
dc.date.accessioned | 2018-09-05T14:48:20Z | - |
dc.date.available | 2018-09-05T14:48:20Z | - |
dc.date.issued | 2018-09 | - |
dc.identifier.citation | Silva, Hélder D.; Poejo, Joana; Pinheiro, Ana Cristina; Donsì, Francesco; Serra, Ana Teresa; Duarte, Catarina M. M.; Ferrari, Giovanna; Cerqueira, Miguel A.; Vicente, António A., Evaluating the behaviour of curcumin nanoemulsions and multilayer nanoemulsions during dynamic in vitro digestion. Journal of Functional Foods, 48, 605-613, 2018 | por |
dc.identifier.issn | 1756-4646 | por |
dc.identifier.uri | https://hdl.handle.net/1822/55757 | - |
dc.description.abstract | Nanoemulsions can be used to improve the bioaccessibility of lipophilic bioactive compounds, such as curcumin, being their behaviour highly influenced by their interfacial properties. The effect of chitosan and alginate layers deposition on curcumin nanoemulsions behaviour during in vitro digestion was evaluated using a dynamic gastrointestinal system. Results showed that polyelectrolyte layers deposition improved curcumin antioxidant capacity during in vitro digestion. In addition, multilayer nanoemulsions showed a better control of the rate and extent of lipid digestibility by decreasing free fatty acids release, compared to uncoated nanoemulsions. However, a lower curcumin bioaccessibility was observed for multilayer nanoemulsions. Although cytotoxicity assays revealed that both nanosystems are toxic due to the use of sodium dodecyl sulphate (SDS), nanosystems were 3.3-fold less toxic than SDS itself. This study showed that multilayer nanoemulsions could be used to increase satiety by retarding lipid digestion, which can be important for functional foods development for combating obesity. | por |
dc.description.sponsorship | The authors Hélder D. Silva, Ana C. Pinheiro and Miguel A. Cerqueira (SFRH/BD/81288/2011, SFRH/BPD/101181/2014 and SFRH/BPD/72753/2010, respectively)aretherecipientsofafellowship from the Fundação para a Ciência e Tecnologia (FCT, Portugal). This work was supported by Portuguese Foundation for Science and Technology (FCT) under the scope of the Project PTDC/AGR-TEC/5215/2014, of the strategic funding of UID/BIO/04469/2013 Unit and COMPETE 2020 (POCI-01-0145-FEDER-006684), BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020 – Programa Operacional Regional do Norte, PEst-OE/EQB/LA0004/2011 and iNOVA4Health – UID/Multi/04462/2013, a program financially supported by FCT/Ministério da Educação e Ciência, through national funds and co-funded by FEDER under the PT2020 Partnership Agreement. The authors also acknowledge the European Commission: BIOCAPS (316265, FP7/REGPOT-2012-2013.1). This work was also supported by the “CARINA” project for the safeness, sustainability and competitiveness of agro-food productions of Campania Region. The support of EU Cost Action FA1001 is gratefully acknowledged. The authors also acknowledge Stepan (The Netherlands) for providing the Neobee 1053 oil, and Rui Fernandes from IBMC, University of Porto for assistance in taking the TEM pictures. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F81288%2F2011/PT | por |
dc.relation | SFRH/BPD/101181/2014 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F72753%2F2010/PT | por |
dc.relation | PTDC/AGR-TEC/5215/2014 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147337/PT | por |
dc.relation | PEst-OE/EQB/LA0004/2011 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147260/PT | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/316265/EU | por |
dc.rights | openAccess | por |
dc.subject | Layer-by-layer | por |
dc.subject | Polyelectrolytes | por |
dc.subject | Multilayer nanoemulsions | por |
dc.subject | Lipid digestion | por |
dc.subject | Bioaccessibility and cytotoxicity | por |
dc.title | Evaluating the behaviour of curcumin nanoemulsions and multilayer nanoemulsions during dynamic in vitro digestion | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.journals.elsevier.com/journal-of-functional-foods | por |
dc.comments | CEB47904 | por |
oaire.citationStartPage | 605 | por |
oaire.citationEndPage | 613 | por |
oaire.citationConferencePlace | Netherlands | - |
oaire.citationVolume | 48 | por |
dc.date.updated | 2018-09-04T16:56:17Z | - |
dc.identifier.doi | 10.1016/j.jff.2018.08.002 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Functional Foods | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_47904_1.pdf | 1,05 MB | Adobe PDF | Ver/Abrir |