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https://hdl.handle.net/1822/50604
Título: | Prediction of adverse pregnancy outcomes by extreme values of first trimester screening markers |
Autor(es): | Gomes, Marina S. Carlos-Alves, Mariana Trocado, Vera Arteiro, Diana Pinheiro, Paula |
Palavras-chave: | Abruptio placentae Fetal growth Human chorionic-gonadotrophin beta-subunit Nuchal translucency Pregnancy-associated plasma protein-A Preeclampsia |
Data: | 24-Mai-2017 |
Editora: | SAGE Publications |
Revista: | Obstetric Medicine |
Citação: | Gomes, M. S., Carlos-Alves, M., Trocado, V., Arteiro, D., & Pinheiro, P. (2017). Prediction of adverse pregnancy outcomes by extreme values of first trimester screening markers. Obstetric medicine, 10(3), 132-137 |
Resumo(s): | Background To determine the association between extreme values of first trimester markers and adverse pregnancy outcomes. Methods A retrospective cohort study of 916 women who underwent first-trimester combined screening during 2015 was performed. Extreme values of NT, pregnancy-associated plasma protein-A (PAPP-A) and free -hCG, and their association with adverse pregnancy outcomes were analyzed. Results Low PAPP-A (<10th percentile) was associated with an increased risk for preeclampsia (adjusted odds ratio (AOR) 4.13), fetal growth restriction (AOR 3.94) and abruptio placentae (AOR 52.63). Abnormally low or high free -hCG, high PAPP-A or increased NT was not associated with an increased risk for adverse outcomes. Discussion PAPP-A <10th percentile could be associated with an increased risk for adverse outcomes. However, the majority of patients with these events do not have abnormal PAPP-A and few patients with PAPP-A <10th percentile will have an adverse outcome. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/50604 |
DOI: | 10.1177/1753495X17704799 |
ISSN: | 1753-495X |
e-ISSN: | 1753-4968 |
Versão da editora: | http://journals.sagepub.com/doi/10.1177/1753495X17704799 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2017 gomesms.pdf | 152,23 kB | Adobe PDF | Ver/Abrir |