Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/48102
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Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Monteiro, Luís S. | por |
dc.contributor.author | Pereira-Lima, Sílvia M. M. A. | por |
dc.contributor.author | Pereira, Sofia | por |
dc.contributor.author | Machado, João N | por |
dc.date.accessioned | 2017-12-07T15:55:27Z | - |
dc.date.available | 2017-12-07T15:55:27Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Luís S. Monteiro, Silvia M. M. A. Pereira-Lima, Sofia Pereira, and João N. Machado, ARKIVOC 2014 (v) 170-180 | por |
dc.identifier.issn | 1551-7012 | por |
dc.identifier.uri | https://hdl.handle.net/1822/48102 | - |
dc.description.abstract | The application of trialkyloxonium tetrafluoroborates for N-alkylation of the nonnatural amino acid Cα, α-dimethylglycine is described. Several methyl esters of dimethylglycine protected with different amine protecting groups were subject to N-ethylation or N-methylation with triethyloxonium tetrafluoroborate or trimethyloxonium tetrafluoroborate, respectively. The corresponding N-akyl-Cα, α-dimethylglycine derivatives were obtained in good to high yields. Removal of the methyl ester rendered amino acid derivatives ready for application in peptide synthesis. | por |
dc.description.sponsorship | Foundation for Science and Technology (FCT) – Portugal and Fundo Europeu de Desenvolvimento Regional (FEDER) for financial support to Chemistry Centre of University of Minho. The NMR spectrometer Bruker Avance II+ 400 is part of the National NMR Network and was purchased in the framework of the National Program for Scientific Re-equipment; contract REDE/1517/RMN/2005, with funds from POCI 2010, FEDER and FCT. | por |
dc.language.iso | eng | por |
dc.publisher | ARKAT USA, Inc. | por |
dc.relation | Fundação para a Ciência e Tecnologia (FCT) | por |
dc.rights | openAccess | por |
dc.subject | Amino acids | por |
dc.subject | nonnatural amino acids | por |
dc.subject | alkylation | por |
dc.subject | N-alkyl-Calpha | por |
dc.subject | alpha-dimethylglycines | por |
dc.title | Synthesis of N-alkyl-C α, α-dimethylglycine derivatives | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.arkat-usa.org/get-file/51110 | por |
oaire.citationStartPage | 170 | por |
oaire.citationEndPage | 180 | por |
oaire.citationIssue | 5 | por |
oaire.citationVolume | v | por |
dc.identifier.eissn | 1551-7004 | por |
dc.identifier.doi | 10.3998/ark.5550190.p008.622 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
sdum.journal | Arkivoc | por |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2014-Arkivoc 170.pdf | 117,25 kB | Adobe PDF | Ver/Abrir |