Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/45187
Título: | Poly(lactic-co-glycolic) acid drug delivery systems through transdermal pathway : an overview |
Autor(es): | Naves, Lucas Dhand, Chetna Almeida, Luís de Rajamani, Lakshminarayanan Ramakrishna, Seeram Soares, Graça M. B. |
Palavras-chave: | Drug delivery system Transdermal drug delivery PLGA Microneedles Electrospinning technique |
Data: | 6-Fev-2017 |
Editora: | SpringerOpen |
Revista: | Progress in biomaterials |
Resumo(s): | In past few decades, scientists have made tremendous advancement in the field of drug delivery systems (DDS), through transdermal pathway, as the skin represents a ready and large surface area for delivering drugs. Efforts are in progress to design efficient transdermal DDS that support sustained drug release at the targeted area for longer duration in the recommended therapeutic window without producing side-effects. Poly(lactic-co-glycolic acid) (PLGA) is one of the most promising Food and Drug Administration approved synthetic polymers in designing versatile drug delivery carriers for different drug administration routes, including transdermal drug delivery. The present review provides a brief introduction over the transdermal drug delivery and PLGA as a material in context to its role in designing drug delivery vehicles. Attempts are made to compile literatures over PLGA-based drug delivery vehicles, including microneedles, nanoparticles, and nanofibers and their role in transdermal drug delivery of different therapeutic agents. Different nanostructure evaluation techniques with their working principles are briefly explained. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/45187 |
DOI: | 10.1007/s40204-017-0063-0 |
ISSN: | 2194-0509 |
Versão da editora: | http://link.springer.com/article/10.1007%2Fs40204-017-0063-0 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | DET/2C2T - Artigos em revistas internacionais com arbitragem científica |
Este trabalho está licenciado sob uma Licença Creative Commons