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https://hdl.handle.net/1822/45052
Título: | Colorectal cancer: comparative analysis of clinical and pathological characteristics in patients aged above and below 45 years of age and impact on prognosis |
Autor(es): | Martins, Sandra Pestana, Joana Sofia Gomes |
Palavras-chave: | Colorectal cancer Age Clinicopathological features Survival |
Data: | Dez-2016 |
Editora: | Sociedade Brasileira de Coloproctologia |
Revista: | Journal of Coloproctology (JCOL) |
Resumo(s): | Introduction Colorectal cancer, in Portugal, presents as the second most common cancer and of cancer death cause. CRC is a disease of the elderly; however, there has been an increase of incidence in younger patients and doubts have emerged about its behavior, characteristics and prognosis in this group. Methods In this study, we have evaluated a sample of 512 patients diagnosed with colorectal cancer submitted to surgical treatment in the period between January 1st, 2005 and January 1st, 2010, through a comparative clinical, pathological and survival analysis of patients under and over 45 years old (Groups I and II respectively). Results Group I patients accounted for 5.5% of the sample. There was a predominance of males and the most common site was the left colon in both age groups. In the younger group, the histological type presents with a predominance of tumors with a mucinous component and with signet ring cells (p = 0.001), however, there was no difference in terms of overall survival and disease-free survival. Conclusion In this study, colorectal cancer at younger ages shows similar characteristics to those of older patients. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/45052 |
DOI: | 10.1016/j.jcol.2016.04.010 |
ISSN: | 2237-9363 |
Versão da editora: | http://www.sciencedirect.com/science/article/pii/S2237936316300351 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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1-s2.0-s2237936316300351-main.pdf | 826,24 kB | Adobe PDF | Ver/Abrir |