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https://hdl.handle.net/1822/44722
Título: | Differentiation of Staphylococcus argenteus (formerly: Staphylococcus aureus clonal complex 75) by mass spectrometry from S. aureus using the first strain isolated from a wild African great ape |
Autor(es): | Schuster, Dominik Rickmeyer, Jasmin Gajdiss, Mike Thye, Thorsten Lorenzen, Stephan Reif, Marion Josten, Michaele Melo, Luís D. R. Schmithausen, Ricarda M. Liégeois, Florian Sahl, Hans-Georg Gonzalez, Jean-Paul J. Nagel, Michael Bierbaum, Gabriele |
Palavras-chave: | Staphylococcus argenteus Staphylococcus aureus Staphylococcus schweitzeri Gorilla gorilla ssp. gorilla MALDI-TOF MS Virulence determinants |
Data: | 2017 |
Editora: | Elsevier 1 |
Revista: | International Journal of Medical Microbiology |
Citação: | Schuster, Dominik; Rickmeyer, Jasmin; Gajdiss, Mike; Thye, Thorsten; Lorenzen, Stephan; Reif, Marion; Josten, Michaele; Melo, Luís D. R.; Schmithausen, Ricarda M.; Liégeois, Florian; Sahl, Hans-Georg; Gonzalez, Jean-Paul J.; Nagel, Michael; Bierbaum, Gabriele, Differentiation of Staphylococcus argenteus (formerly: Staphylococcus aureus clonal complex 75) by mass spectrometry from S. aureus using the first strain isolated from a wild African great ape. International Journal of Medical Microbiology, 307(1), 57-63, 2017 |
Resumo(s): | The species Staphylococcus argenteus was separated recently from Staphylococcus aureus (Tong S.Y., F. Schaumburg, M.J. Ellington, J. Corander, B. Pichon, F. Leendertz, S.D. Bentley, J. Parkhill, D.C. Holt, G. Peters, and P.M. Giffard, 2015). The objective of this work was to characterise the genome of a non-human S. argenteus strain, which had been isolated from the faeces of a wild-living western lowland gorilla in Gabon, and analyse the spectrum of this species in matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). The full genome sequence revealed a scarcity of virulence genes and absence of resistance genes, indicating a decreased virulence potential compared to S. aureus and the human methicillin-resistant S. argenteus isolate MSHR1132T. Spectra obtained by MALDI-TOF MS and the analysis of available sequences in the genome databases identified several MALDI-TOF MS signals that clearly differentiate S. argenteus, the closely related Staphylococcus schweitzeri and S. aureus. In conclusion, in the absence of biochemical tests that identify the three species, mass spectrometry should be employed as method of choice. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/44722 |
DOI: | 10.1016/j.ijmm.2016.11.003 |
ISSN: | 1618-0607 |
e-ISSN: | 1438-4221 |
Versão da editora: | http://www.journals.elsevier.com/international-journal-of-medical-microbiology/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_46581_1.pdf | 703,86 kB | Adobe PDF | Ver/Abrir |