Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/39146
Título: | Microencapsulation of ellagic acid from pomegranate husk and karaya gum by spray drying |
Autor(es): | Luján-Medina, Gabriel A. Ventura, Janeth Ascacio-Valdés, Juan A. Cerqueira, M. A. Villa, Daniel Boone Contreras-Esquivel, Juan C. González, Miguel A. Aguilar Vicente, A. A. Aguilar, Cristóbal N. |
Palavras-chave: | Pomegranate husk Ellagic acid Karaya gum Spray drier Microcapsules |
Data: | 2015 |
Editora: | World Academy of Science, Engineering and Technology (WASET) |
Revista: | International Journal of Pharmacy and Pharmaceutical Sciences |
Citação: | Luján-Medina, Gabriel A.; Ventura, Janeth; Ascacio-Valdés, Juan A.; Cerqueira, M. A.; Villa, Daniel Boone; Contreras-Esquivel, Juan C.; González, Miguel A. Aguilar; Vicente, A. A.; Aguilar, Cristóbal N., Microencapsulation of ellagic acid from pomegranate husk and karaya gum by spray drying. International Journal of Pharmacy and Pharmaceutical Sciences, 7(Suppl. 1), 212-216, 2015 |
Resumo(s): | Objective: The aim of this study was to obtain and characterize microcapsules with Ellagic Acid (EA) from pomegranate as core material and Karaya Gum (KG) as wall material. Methods: EA was obtained from dry pomegranate peel powder via methanolysis and quantified by HPLC. Microcapsules were obtained preparing a dispersion containing KG and EA in phosphate buffer pH 8. The dispersion was processed in a spray dryer under specific conditions (inlet temperature at 150 °C, feed flow at 30% and aspirator at 100 %) for obtaining of microcapsules. Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC) and scanning electron microscopy (SEM) were used for characterization. Results: Obtained material contains 98.03±2.82 mg EA/g of pomegranate peel. FTIR showed that there were changes in the molecular structure of microcapsules referred to raw materials. SEM confirmed that particles obtained had micron-size (1-5 µm). DSC analysis showed that raw materials had glass transition temperatures of 79.58 and 83.41 °C and for microcapsules the value was67.25 °C. Conclusion: Methanolysis is a viable technique for the obtaining of EA from the peel of pomegranate. KG shows good potential for be used as wall material for EA microencapsulation. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/39146 |
ISSN: | 0975-1491 |
Versão da editora: | http://innovareacademics.in/journals/index.php/ijpps/index |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
document_26645_1.pdf | 504,26 kB | Adobe PDF | Ver/Abrir |