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https://hdl.handle.net/1822/29136| Título: | Genetics and molecular epidemiology of multiple myeloma : the rationale for the IMMEnSE consortium (review) |
| Autor(es): | Martino, Alessandro Sainz, Juan Buda, Gabriele Jamroziak, Krzysztof Reis, R. M. García-Sanz, Ramón Jurado, Manuel Ríos, Rafael Szemraj-Rogucka, Zofia Marques, Herlander Lesueur, Fabienne Moreno, Victor Orciuolo, Enrico Gemignani, Federica Landi, Stefano Rossi, Anna Maria Dumontet, Charles Petrini, Mario Campa, Daniele Canzian, Federico |
| Palavras-chave: | IMMEnSE consortium Multiple myeloma SNPs Genetic susceptibility Pharmacogenetics |
| Data: | 2012 |
| Editora: | Spandidos Publications |
| Revista: | International journal of oncology |
| Resumo(s): | There is strong evidence suggesting the presence of a genetic component in the aetiology of multiple myeloma (MM). However no genetic risk factors have been unequivocally established so far. To further our understanding of the genetic determinants of MM risk, a promising strategy is to collect a large set of patients in a consortium, as successfully done for other cancers. In this article, we review the main findings in the genetic susceptibility and pharmacogenetics of MM and present the strategy of the IMMEnSE (International Multiple Myeloma rESEarch) consortium in contributing to determine the role of genetic variation in pharmacogenetics and in MM risk. |
| Tipo: | Artigo |
| URI: | https://hdl.handle.net/1822/29136 |
| DOI: | 10.3892/ijo.2011.1284 |
| ISSN: | 1019-6439 1791-2423 |
| Versão da editora: | http://www.spandidos-publications.com/ijo/40/3/625 |
| Arbitragem científica: | yes |
| Acesso: | Acesso aberto |
| Aparece nas coleções: |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| martino alessandro_int j oncol. 2012--ok.pdf | 499,34 kB | Adobe PDF | Ver/Abrir |
