Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/27327
Título: | Neuronal cells’ behavior on polypyrrole coated bacterial nanocellulose three-dimensional (3D) scaffolds |
Autor(es): | Muller, Daliana Silva, João P. Rambo, C. Barra, G. Dourado, Fernando Gama, F. M. |
Palavras-chave: | Bacterial cellulose Biomaterials bacterial nanocellulose neuronal cells polypyrrole 3D cell culture nanofibrous scaffolds |
Data: | 2013 |
Editora: | Taylor and Francis |
Revista: | Journal of Biomaterials Science. Polymer Edition |
Resumo(s): | In this work, polypyrrole (PPy) was in situ polymerized onto the surface of bacterial nanocellulose (BNC) produced by Gluconacetobacter xylinus, by chemical oxidation in aqueous medium using ammonium persulfate. Composites (BNC/PPy) were produced with varying concentrations of pyrrole (Py). The produced BNC/PPy membranes were used as a template for the seeding of PC12 rat neuronal cells. Cell suspensions were directly seeded onto the surfaces of the BNC/PPy membranes. The Py concentration affected the behavior of neuronal cells that adhered and grew significantly more on BNC/PPy comparatively to BNC. Scanning electron microscopy (SEM) micrographs revealed that PC12 cells adhered on the surface of the BNC and BNC/PPy membranes. Conductive PPy coatings on nanofibers acting as an active interface for tissue engineering may be used to regulate cell activity through electrical stimulations. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/27327 |
DOI: | 10.1080/09205063.2012.761058 |
ISSN: | 0920-5063 |
e-ISSN: | 1568-5624 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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BC-PPy-PC12-Muller et al-2013.pdf Acesso restrito! | 419,83 kB | Adobe PDF | Ver/Abrir |