Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/23780
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Campo DC | Valor | Idioma |
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dc.contributor.author | Beldi, Mariana Carmezim | - |
dc.contributor.author | Tacla, Maricy | - |
dc.contributor.author | Caiaffa-Filho, Helio | - |
dc.contributor.author | Ab’Saber, Alexandre | - |
dc.contributor.author | Siqueira, Sheila | - |
dc.contributor.author | Baracat, Edmund Chada | - |
dc.contributor.author | Alves, Venâncio Avancini Ferreira | - |
dc.contributor.author | Longatto Filho, Adhemar | - |
dc.date.accessioned | 2013-04-23T12:53:09Z | - |
dc.date.available | 2013-04-23T12:53:09Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0001-5547 | por |
dc.identifier.uri | https://hdl.handle.net/1822/23780 | - |
dc.description | Author's proof. The authors are indebted to Luciane Sarahyba and Nazareno dos Santos of the Molecular Biology Laboratory for their technical assistance. | por |
dc.description.abstract | OBJECTIVES: Robust evidence now supports human papillomavirus (HPV) testing as a more effective option to screening and as more sensitive than cytology in detecting high-grade cervical intraepithelial neoplasia . Our goal was to analyze the performance of the Hybrid Capture II (HC2) assay for high-risk HPV (hrHPV) in women undergoing gynecological examination at a public health hospital as part of the evaluation of HPV screening as an alternative or complement to cytology. STUDY DESIGN: This analysis is a subset of a cross-sectional study carried out at a large public hospital serving a predominantly low-resource population. A total of 705 women were enrolled; the sensitivity and specificity of each test were estimated and compared. RESULTS: The analysis identified 272 hrHPV-positive women (mean age 36.3 years) and 433 hrHPV-negative women (mean age 41.2 years). HPV testing showed a significantly increased sensitivity of the HC2 assay versus cytology (84.5 vs. 69.7%; p < 0.0001) but a lower specificity (49.90 vs. 88.78%; p < 0.0001). CONCLUSION: The combination of both methods seems to be useful in improving detection of cervical lesions. | por |
dc.language.iso | eng | por |
dc.publisher | Karger AG | por |
dc.rights | openAccess | por |
dc.subject | Cytology | por |
dc.subject | Pap test | por |
dc.subject | Human papillomavirus testing | por |
dc.subject | Primary screening | por |
dc.title | Implementing human papillomavirus testing in a public health hospital : challenges and opportunities | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | www.karger.com/acy | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 160 | por |
oaire.citationEndPage | 165 | por |
oaire.citationIssue | 2 | por |
oaire.citationTitle | Acta Cytologica | por |
oaire.citationVolume | 56 | por |
dc.identifier.doi | 10.1159/000335145 | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Acta Cytologica | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Beldi M_Acta Cytologica 2012 pp.pdf | Author's proof | 216,24 kB | Adobe PDF | Ver/Abrir |