Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/2239| Título: | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series : a structure-activity evaluation study |
| Autor(es): | Ferreira, Isabel C. F. R. Calhelha, Ricardo C. Estevinho, Letícia M. Queiroz, Maria João R. P. |
| Palavras-chave: | Diarylamines Antimicrobial activity SAR Benzothiophenes |
| Data: | 2004 |
| Editora: | Elsevier 1 |
| Revista: | Bioorganic & Medicinal Chemistry Letters |
| Citação: | “Bioorganic and medical chemistry letters”. 14 (2004) 5831-5833. |
| Resumo(s): | Gram positive (Bacillus cereus, Bacillus subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethyl benzo[b]thiophene series bearing different substituents, synthesised by us using the palladium-catalyzed C-N coupling methodology. The minimal inhibitory concentration (MIC) and structure-activity relationships (SARs) were evaluated. |
| Tipo: | Artigo |
| URI: | https://hdl.handle.net/1822/2239 |
| DOI: | 10.1016/j.bmcl.2004.09.038 |
| ISSN: | 0960-894X |
| Arbitragem científica: | yes |
| Acesso: | Acesso aberto |
| Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| ICF-Biorg.pdf | 36,85 kB | Adobe PDF | Ver/Abrir |
