Photoresponsive prodrugs of butyric acid based on amino naphthopyranones

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/21980

Registo completo

Campo DC	Valor	Idioma
dc.contributor.author	Soares, Ana M. S.	-
dc.contributor.author	Costa, Susana P. G.	-
dc.contributor.author	Gonçalves, M. Sameiro T.	-
dc.date.accessioned	2012-12-21T14:51:19Z	-
dc.date.available	2012-12-21T14:51:19Z	-
dc.date.issued	2012	-
dc.identifier.uri	https://hdl.handle.net/1822/21980	-
dc.description.abstract	In order to evaluate the application of new 7-amino-naphtho[1,2-b]pyran-2-ones as photoactive groups in the preparation of carboxylic acid derivatives, model butyric ester conjugates were synthesised by reaction with the chloromethylated heterocyclic precursor. Photocleavage studies of the ester conjugates in methanol/HEPES buffer (80:20) solution at different wavelengths of irradiation (254, 300, 350 and 419 nm) confirmed the quantitative release of the model acid in short irradiation times.	por
dc.description.sponsorship	Fundação para a Ciência e Tecnologia (FCT, Portugal) - financial support to the NMR portuguese network (PTNMR, Bruker Avance III 400-Univ. Minho), FCT and FEDER (European Fund for Regional Development)-COMPETE-QREN-EU for financial support to the Research Centre CQ/UM [PEst-C/QUI/UI0686/2011 (FCOMP-01-0124-FEDER-022716)]. FCT: PhD grant - A.M.S.S. (SFRH/BD/80813/2011).	por
dc.language.iso	eng	por
dc.rights	restrictedAccess	por
dc.subject	Prodrugs	por
dc.subject	Butyric acid	por
dc.subject	Coumarin	por
dc.subject	Naphthopyranone	por
dc.subject	Photolysis	por
dc.title	Photoresponsive prodrugs of butyric acid based on amino naphthopyranones	por
dc.type	conferencePaper	-
dc.peerreviewed	yes	por
dc.relation.publisherversion	http://www.sciforum.net/conf/ecsoc-16	por
sdum.publicationstatus	in publication	por
oaire.citationConferenceDate	.	por
sdum.event.type	conference	por
oaire.citationTitle	The 16th International Electronic Conference on Synthetic Organic Chemistry	por
sdum.conferencePublication	The 16th International Electronic Conference on Synthetic Organic Chemistry	por
Aparece nas coleções:	CDQuim - Comunicações e Proceedings

Ficheiros deste registo:

Ficheiro	Descrição	Tamanho	Formato
Proceeding-AMS.pdf Acesso restrito!	Final draft post-refereeing	257,49 kB	Adobe PDF	Ver/Abrir

Ver registo simples Sugerir correção Estatísticas