Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/2182
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Ragnarsson, Ulf | - |
dc.contributor.author | Grehn, Leif | - |
dc.contributor.author | Maia, Hernâni L. S. | - |
dc.contributor.author | Monteiro, Luís S. | - |
dc.date.accessioned | 2005-06-14T10:43:11Z | - |
dc.date.available | 2005-06-14T10:43:11Z | - |
dc.date.issued | 2002 | - |
dc.identifier.citation | “Journal of the chemical society. Perkin transactions”. 1 (2002) 97-101. | eng |
dc.identifier.issn | 1472-7781 | por |
dc.identifier.uri | https://hdl.handle.net/1822/2182 | - |
dc.description.abstract | Synthetic and spectroscopic details related to a set of heteroaromatic N-benzyl carboxamides and especially the corresponding tert-butyl acylcarbamates are reported. These compounds were required to study the postulated effect of various heterocycles (pyridine and pyrazine with and without condensed benzene rings) on the cleavage of acyl-N bonds by reduction. All compounds were initially characterized by cyclic voltammetry which indicated various degrees of facilitated reduction, reflecting a direct influence of the heterocyclic component. Selected acylcarbamates were studied with respect to acyl-N bond cleavage by mild reducing agents and selectively deacylated by activated aluminium and sodium borohydride. Conversion to acylcarbamates followed by reduction might therefore be a mild, efficient two-step procedure to effect cleavage of amides, allowing isolation of carbamates and with sodium borohydride also the corresponding alcohols. | eng |
dc.description.sponsorship | Fundação para a Ciência e Tecnologia. NFR and Magnus Bergvalls Stiftelse. RSC. TFR. | por |
dc.language.iso | eng | eng |
dc.publisher | Royal Society of Chemistry | eng |
dc.rights | openAccess | eng |
dc.title | Reductive cleavage of N-substituted aromatic amides as tert-butyl acylcarbamates | eng |
dc.type | article | eng |
dc.peerreviewed | yes | eng |
oaire.citationStartPage | 97 | por |
oaire.citationEndPage | 101 | por |
oaire.citationIssue | 1 | por |
oaire.citationVolume | 2 | por |
dc.identifier.doi | 10.1039/b107330n | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of the Chemical Society, Perkin Transactions 1 | por |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2002-J. Chem. Soc. Perkin 1.pdf | 106,77 kB | Adobe PDF | Ver/Abrir |