Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/1757
Título: | Contamination of a high-cell-density continuous bioreactor |
Autor(es): | Domingues, Lucília Lima, Nelson Teixeira, J. A. |
Palavras-chave: | Airlift bioreactor Continuous operation Flocculent S. cerevisiae Bacterial contamination |
Data: | Jun-2000 |
Editora: | John Wiley and Sons |
Revista: | Biotechnology and Bioengineering |
Citação: | "Biotechnology bioengineering". 68:5 (2000) 584-587. |
Resumo(s): | Continuous fermentations were carried out with a recombinant flocculent Saccharomyces cerevisiae strain in an airlift bioreactor. Once operating under steady state at a dilution rate of 0.45 h−1, the bioreactor was contaminated with Escherichia coli cells. The faster growing E. coli strain was washed out of the bioreactor and the recombinant, slower growing flocculating S. cerevisiae strain remained as the only species detected in the bioreactor. Flocculation, besides allowing for the realization of high-cell-density systems with corresponding unusual high productivity, may be used as a selective property for controlling some contamination problems associated with prolonged continuous operation. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/1757 |
DOI: | 10.1002/(SICI)1097-0290(20000605)68:5<584::AID-BIT14>3.0.CO;2-1 |
ISSN: | 0006-3592 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series DCILM - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2000-10[1].pdf | 73,18 kB | Adobe PDF | Ver/Abrir |