Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/16201
Título: | Presmoothing the transition probabilities in the illness-death model |
Autor(es): | Amorim, Ana Paula Uña Álvarez, Jacobo de Machado, Luís Meira |
Palavras-chave: | Kaplan–Meier Markov condition Multi-state models Semiparametric censorship |
Data: | Jul-2011 |
Editora: | Elsevier 1 |
Revista: | Statistics & Probability Letters |
Resumo(s): | One major goal in clinical applications of multi-state models is the estimation of transition probabilities. In a recent paper, Meira-Machado et al. (2006) introduce a substitute for the Aalen–Johansen estimator in the case of a non-Markov illness–death model. The idea behind their estimator is to weight the data by the Kaplan–Meier weights pertaining to the distribution of the total survival time of the process. In this paper we propose a modification of Meira-Machado et al. (2006) estimator based on presmoothing. Consistency is established. We investigate the finite sample performance of the new estimator through simulations. Data from a study on colon cancer are used for illustration purposes. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/16201 |
DOI: | 10.1016/j.spl.2011.02.017 |
ISSN: | 0167-7152 |
Versão da editora: | http://www.journals.elsevier.com/statistics-and-probability-letters/ |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CMAT - Artigos em revistas com arbitragem / Papers in peer review journals DMA - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Statistics_P_Letters.pdf Acesso restrito! | Documento principal | 503,72 kB | Adobe PDF | Ver/Abrir |