Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/16016
Título: | Monocarboxylate transporters: new molecular targets for colorectal carcinoma |
Autor(es): | Amorim, Ricardo Martins, Sandra Pereira, Helena Paula Fernandes Pinheiro, Céline Reis, R. L. Longatto Filho, Adhemar Preto, Ana Baltazar, Fátima |
Data: | 2011 |
Resumo(s): | [Excerpt] Colorectal carcinoma (CRC) is the second leading cause of cancer-related death in industrialized countries1. 5-Fluorouracil (5-FU) is one of the most efficient chemotherapeutic agents in the treatment of CRC although resistance to 5-FU treatment has been reported2. CRC relies mostly on glycolysis to meet their energetic demands and, as a consequence, CRC cells produce large amounts of lactate that must be extruded to the tumour microenvironment by lactate transporters, namely monocarboxylate transporters (MCTs). (...) |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/16016 |
Arbitragem científica: | no |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | DBio - Comunicações/Communications in Congresses |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Abstract México (FINAL).pdf Acesso restrito! | Documento principal | 196,79 kB | Adobe PDF | Ver/Abrir |