Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/15324
Título: | Spectra optical detection of biomolecules using a white light source-based spectrophotometric platform |
Autor(es): | Cardoso, Susana Freitas, Paulo Miranda, Adelaide Ferreira, D. S. Minas, Graça |
Palavras-chave: | Thin-film optical filters Spectrophotometric analysis Lab-on-a-chip White light |
Data: | 28-Out-2011 |
Editora: | IEEE |
Revista: | Proceedings of IEEE Sensors |
Resumo(s): | This work describes the integration of thin-film optical filters in a lab-on-a-chip device for spectrophotometric analysis of biological fluids using white-light as illumination. Thin-film SiO2/TiO2 multilayers were optimized according to numerical simulations, so that the optical transmittance is tuned for specific wavelengths. These films were deposited on glass substrates by Ion Beam and then integrated in a previously developed lab-on-a-chip platform, which incorporates microfluidic and detection modules. The system operates with a white-light source that is filtered to a narrow spectral band, centred at the desired wavelength, allowing the selective measurement of the light intensity transmitted through the fluid. This intensity is quantified using a colorimetric detection system and then correlated with the biomolecule concentration. Several calcium concentrations in urine were successfully detected in the lab-on-a-chip using the filtering system. |
Tipo: | Artigo em ata de conferência |
URI: | https://hdl.handle.net/1822/15324 |
ISBN: | 9781424492886 |
DOI: | 10.1109/ICSENS.2011.6127366 |
ISSN: | 1930-0395 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | DEI - Artigos em atas de congressos internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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IEEE sensors2011.pdf Acesso restrito! | Documento principal | 367,13 kB | Adobe PDF | Ver/Abrir |